Disease marker combination enhances patient characterization in the Finnish sarcoidosis patients
Sarcoidosis is an inflammatory disease of unknown etiology and multiple clinical phenotypes. Clinical manifestations range from asymptomatic disease to severe loss-of-function leading to the hypothesis that sarcoidosis might not be just one disease, but consists of several distinct disease entities each with potentially distinct genetic associations. We have previously demonstrated that in our series HLADRB1* 03:01 and haplotype HLA-DRB1*04:01-DPB1*04:01 are associated with good prognosis sarcoidosis.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: E. Lahtela, A. Wolin, A. Pietinalho, M.-L. Lokki, O. Selroos Tags: Short communication Source Type: research