Significant bone loss after stopping long-term denosumab treatment: a post FREEDOM study

ConclusionOur results describe the rapid bone loss occurring after cessation of denosumab treatment. Further studies are needed to assess if patients have a higher risk of fracture after stopping DMAb and if so, which patients have the highest risk, and assess the role of transitioning to bisphosphonates in the long term.

http://link.springer.com/10.1007/s00198-017-4242-6

Source: Osteoporosis International - October 3, 2017 Category: Orthopaedics Source Type: research