Montelukast Adds Little For Elderly Asthma Patients

Montelukast for 8 weeks appeared to reduce daily symptoms scores and number of puffs of albuterol relative to placebo, but the results did not reach statistical significance. But....there are caveats.
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Asthma Respiratory Diseases Source Type: news

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Authors: Scheffer-Rath ME, Boot AM Abstract Vitamin D is important for skeletal growth, bone mineralization and dental health. Vitamin D deficiency is reported in many countries, may have several causes and can cause rickets in children. A guideline with recommendations of vitamin D supplementation to prevent nutritional rickets was published recently. The vitamin D receptor is present in many cells of the body including cells of the immune system. Many studies have been published on associations between vitamin D deficiency and extra skeletal effects, mainly without proof of causality in intervention studies. This...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
Authors: Ueta Y, Akiba Y, Yamazaki J, Okubo Y, Taguchi T, Terashi H, K Hayashi Y, Aizawa H Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare condition of systemic vasculitis of small to medium-sized blood vessels. We herein report the case of a 75-year-old man who presented with hemiplegia on his right side due to cerebral infarction following myalgia and a high fever. He had no history of asthma or allergic rhinitis. He was diagnosed with EGPA based on the presence of eosinophilia, sinusitis suggested by magnetic resonance imaging, and muscle pathology. His hemiplegia improved rapidly after c...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Abstract The lung is a mechanically active organ, but uncontrolled or excessive mechanical forces disrupt normal lung function and can contribute to the development of disease. In asthma, bronchoconstriction leads to airway narrowing and airway wall buckling. A growing body of evidence suggests that pathological mechanical forces induced by airway buckling alone can perpetuate disease processes in asthma. Here, we review the data obtained from a variety of experimental models, including in vitro, ex vivo and in vivo approaches, which have been used to study the impact of mechanical forces in asthma pathogenesis. W...
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Eur Respir Rev Source Type: research
Publication date: Available online 12 August 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Li-ming Zhu, Dan Zeng, Xue-chun Lei, Jin Huang, Yan-feng Deng, Yu-bin Ji, Jing Liu, Fang-fang Dai, Yu-zhu Li, Dan-dan Shi, Ying-qun Zhu, Ai-guo Dai, Zi Wang
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Conditions:   Asthma;   Obesity Intervention:   Drug: Hyperpolarized 129XeMRI Sponsors:   Bastiaan Driehuys;   National Institutes of Health (NIH) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Asthma; Eosinophilic Intervention:   Drug: Mepolizumab Sponsors:   Hannover Medical School;   GlaxoSmithKline Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: The obtained results may indicate the need to offer patients with respiratory diseases psychotherapeutic activities aimed at building a more constructive functioning, reducing anxiety, increasing the sense of control. PMID: 32772062 [PubMed - in process]
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Authors: Jowik K, Dutkiewicz A, Słopień A, Tyszkiewicz-Nwafor M Abstract Eating disorders (ED) constitute the third most common group of chronic diseases among people aged 14-19 years after asthma and obesity, and one of their forms is binge eating disorder (BED). The purpose of the present review was to summarize new research findings on BED and overview the epidemiology, characteristics, criteria, etiopathogenesis, and treatment. Etiopathogenesis of BED is still poorly understood, and the current state of knowledge leads to the conclusion that the pathomechanism of the development and persistence of the symptom...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Publication date: Available online 11 August 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Yu Yu Han, Xin Zhang, Ji Wang, Gang Wang, Brian G. Oliver, Hong Ping Zhang, De Ying Kang, Lei Wang, Zhi Xin Qiu, Wei Min Li, Gang Wang
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 6 August 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Karen B. Evaristo, Felipe Augusto Rodrigues Mendes, Milene G. Saccomani, Alberto Cukier, Regina M. Carvalho-Pinto, Marcos R. Rodrigues, Danilo F. Santaella, Beatriz M. Saraiva-Romanholo, Milton A. Martins, Celso R.F. Carvalho
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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