Prevention of Progression in Multiple Myeloma

NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Irene Ghobrial is an Associate Professor at Dana-Farber Cancer Institute (DFCI), Harvard Medical School, Boston, MA and an Associate member of the Broad Institute, Cambridge, MA. She is the director of the Michele& Stephen Kirsch Laboratory and co-director of the Center for Prevention of Progression of Blood Cancers (CPOP) at DFCI. In addition, she is the co-leader of the Blood Cancer Research Partnership (BCRP), a consortium for innovative clinical trials of community oncology sites coordinated by DFCI. Dr. Ghobrial received her medical degree from Cairo University School of Medicine, Egypt. She completed her internal medicine training at Wayne State University, MI, and her hematology/oncology sub-specialty training at Mayo Clinic College of Medicine, MN. Her research focuses on understanding mechanisms of tumor progression from early precursor conditions such as monoclonal gammopathy of undetermined significance (MGUS) and Smoldering disease to symptomatic Multiple Myeloma (MM) and Waldenstr รถ m Macroglobulinemia (WM). She specifically focuses on the role of the malignant bone marrow niche in regulating disease progression. She is interested in the development of new molecular/genomic markers that predict progression in precursor conditions which can identify patients who should be eligible for therapeutic interventions to prevent progression or potentially cure the disease at the early stages of the disease before cl...
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