Finding ideal blood pressure targets in ischaemic stroke: prospective insight or retrospective guesswork?

This editorial refers to ‘Blood pressure and in-hospital outcomes in patients presenting with ischaemic stroke’†, by S. Bangaloreet al., on page2827.
Source: European Heart Journal - Category: Cardiology Source Type: research

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Publication date: Available online 22 September 2020Source: NeuroscienceAuthor(s): Qian Jiang, Xiaokun Geng, Johnathan Warren, Eric Eugene Paul Cosky, Shawn Kaura, Christopher Stone, Fengwu Li, Yuchuan Ding
Source: Neuroscience - Category: Neuroscience Source Type: research
We report a case of ischemic stroke in the area of a DVA after minor...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Nature Reviews Neurology, Published online: 23 September 2020; doi:10.1038/s41582-020-00417-0Despite the strong treatment effects of mechanical thrombectomy in acute ischaemic stroke, penumbral tissue loss before recanalization and ischaemia–reperfusion injury after diminish functional outcomes and call for adjunct treatments. Classical neuroprotection strategies could consequently be revived, but novel treatment targets are also emerging through mechanistic research.
Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research
AbstractBackgroundWomen undergoing atrial fibrillation catheter ablation (AFCA) have higher rates of vascular complications and major bleeding. However, most studies have been underpowered to detect differences in rarer complications such as stroke/transient ischemic attack (TIA) and procedural mortality.MethodsWe performed a systematic review of databases (PubMed, World of Science, Embase) to identify studies published since 2010 reporting AFCA complications by sex. Six complications of interest were: 1) vascular/groin complications; 2) pericardial effusion/tamponade; 3) stroke/TIA; 4) permanent phrenic nerve injury; 5) m...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research
ConclusionsThe H-REPLACE trial offers an opportunity to assess clinical outcomes of rivaroxaban versus enoxaparin during the acute phase of ACS and may provide an alternative anticoagulation strategy for ACS patients, who missed the primary reperfusion therapy window and before selective revascularization.Trial RegistrationClinicalTrials.gov; NCT03363035.
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
Authors: Banham ND, Saw J, Hankey GJ, Ghia D Abstract A 75 year-old male developed features of an acute stroke following bubble contrast echocardiography, which was shown on emergent computed tomography scanning to be a result of cerebral arterial gas embolism (CAGE) to the left middle cerebral artery. Ischaemic stroke symptoms have previously been reported as a rare complication of bubble contrast echocardiography. Radiologically proven CAGE from bubble contrast echocardiography had not been reported at the time this case occurred. Immediate provision of 100% oxygen and administration of hyperbaric oxygen are reco...
Source: Diving and Hyperbaric Medicine - Category: Sports Medicine Tags: Diving Hyperb Med Source Type: research
Condition:   Stroke, Ischemic Interventions:   Other: Traditional physical therapy balance exercise;   Other: proprioception based balance training Sponsor:   Riphah International University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Pan H, Zhao R, Liu FD, Wu YL, Li GF, Shi YH, Liu YS, Zhao Y, Zhuang MT, Hou TY, Zhang QT, Yao Q, Qiao Y, Huang RJ, Chen LN, Zhu YM, Shu L, Su JJ, Fang J, Tang XM, Wang S, Cui GH, Wang DZ, Liu JR Abstract Our aim was to investigate factors predicting blood pressure (BP) variability during diagnostic cerebral angiography and associations between BP variability and clinical outcomes in patients with acute and subacute ischemic stroke and intracranial artery stenosis. 114 patients with ischemic stroke and intracranial artery stenosis (stenosis rate>50%) were recruited. Patients who underwent cerebral angiog...
Source: International Journal of Hypertension - Category: Cardiology Tags: Int J Hypertens Source Type: research
TUESDAY, Sept. 22, 2020 -- Exposure to air pollution may increase the risk for ischemic stroke in patients with atrial fibrillation (AF), according to a study published online Sept. 15 in JAMA Network Open. Zachary J. Rhinehart, M.D., from the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Authors: Wang Q, Liu X, Zhao J, Zhu R Abstract INTRODUCTION: Ischemic stroke is a life-threatening condition worldwide, including China. Nowadays, intravenous thrombolysis and mechanical thrombectomy are chiefly applied as clinical therapeutics; however, strict time windows and underlying risks limit their benefits for patients. Thus, it is urgently needed to seek new effective targets for stroke to improve clinical outcomes. AREAS COVERED: Circular RNAs have recently emerged as ideal therapeutic candidates for ischemic stroke with high stability and evolutionary conservation in the brain tissue. The neurovascu...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
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