Structural anomalies of the peripheral olfactory system in psychosis high-risk subjects

Olfactory impairments are prominent in both schizophrenia and the preceding at-risk state. Their presence prior to illness predicts poor functional outcome. In schizophrenia, these impairments reflect peripheral olfactory structural abnormalities, which are hypothesized to arise during early embryonic development. If this is correct, then similar structural anomalies should be apparent among clinical high-risk subjects.

Source: Schizophrenia Research - September 30, 2017 Category: Psychiatry Authors: Bruce I. Turetsky, Paul J. Moberg, Megan Quarmley, Erich Dress, Monica E. Calkins, Kosha Ruparel, Karthik Prabhakaran, Raquel E. Gur, David R. Roalf Source Type: research