Heat stress induced, ligand-independent MET and EGFR signaling in hepatocellular carcinoma.

CONCLUSIONS: Heat stress induced MET and EGFR signaling is distinct from growth factor mediated signaling in HCC cells and MET inhibition enhances heat stress induced HCC cell killing via a PI3K/AKT/mTOR-independent mechanism. PMID: 28954551 [PubMed - as supplied by publisher]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research