Vitamin B No Help for Alzheimer's: Review

Title: Vitamin B No Help for Alzheimer's: ReviewCategory: Health NewsCreated: 7/16/2014 4:36:00 PMLast Editorial Review: 7/17/2014 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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Abstract Identification of tyrosine Fyn kinase inhibitor is recognized as an effective and feasible therapeutic measure in reducing consequences of memory loss disorder Alzheimer's. The present investigation has been attempted with an objective to find out a novel potent inhibitor with similar homological structure to Fyn kinase using structure based in silico screening measure. Such derived structure was compared with natural data base pool and were systematically analyzed. Ligand based interaction was also tested and evaluated. We applied a molecular dynamic simulation technique to validate the stability of the ...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Authors: Lu X, Yang B, Yu H, Hu X, Nie J, Wan B, Zhang M, Lü C Abstract Context: Neuroligin-1 (NLGN1) is a cell adhesion protein located on the excitatory postsynaptic membrane. β-Amyloid (Aβ)-induced neuroinflammation decreases NLGN1 expression through epigenetic mechanisms. Triptolide (T10) and tripchlorolide (T4) exert protective effects on synapses in Alzheimer's disease (AD) mice, but the mechanisms remain unclear. Objective: The effects of T10 and T4 on hippocampal NLGN1 expression in AD mice and the epigenetic mechanisms were assessed using chromatin immunoprecipitation and methylated DNA immu...
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s): Zaven S. Khachaturian, Lewis H. Kuller, Ara S. Khachaturian
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
This article summarizes the evidence for translation into action.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
DiscussionEducation did not convey differential survival advantages to individuals with higher genetic risk of AD, but may reduce hospitalization risk associated with AD genetic risk.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: July 2019Source: Alzheimer's &Dementia, Volume 15, Issue 7Author(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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