Heart drug niacin may pose serious health risks
Research has found a troubling rise in deaths among people who use popular drug to manage cholesterol
Authors: Avcil S Abstract BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, which is multifactorial, complex, and seen most commonly in childhood. AIMS: The aim of this study was to examine the hypothesis that altered serum lipid profiles are associated with ADHD. METHODS: The study inluded 32 boys diagnosed with ADHD according to DSM-IV-R criteria and a control group of 29 healthy subjects. All patients were assessed with The Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version, the Turgay DSM-IV-based Disruptive Behavior Disorde...
The Vascular Study Group of Greater New York (VSGGNY) database was used to identify all patients undergoing peripheral vascular intervention or lower extremity bypass for peripheral arterial disease (PAD; 2011-2013).
Although carotid endarterectomy and stenting for symptomatic significant carotid artery stenosis are widely accepted for stroke prevention, their use for asymptomatic stenosis is more controversial. With the advances in medical therapy, particularly the use of statins, and with an annual stroke risk of 1% to 2% for asymptomatic disease, justifying these interventions in these patients is more difficult. What is more disturbing is that ∼90% of all carotid endarterectomy and stenting procedures in the United States are performed on asymptomatic patients and that many were felt to be unnecessary, resulting in a cost of>...
The optimum method for screening for dyslipidemia in children and adolescents has been controversial. In many European countries, cascade screening is used. This approach starts with identification of an adult with dyslipidemia and then screens other family members. Historically, in the United States, an approach based on family history was used, but research demonstrated that this approach missed many children and adolescents with substantial elevation of LDL-C. This led to the suggestion that a universal screening approach, in which children have their cholesterol measured once, was a better option.
To compare the number of children needed to screen to identify a case of childhood dyslipidemia and estimate costs under universal vs targeted screening approaches.
No abstract available
Conclusion: Further studies are needed to understand the role of sclerostin in predicting PWV changes in HD patients.Blood Purif 2018;46:118 –125
CONCLUSION: mevalonate pathway can be exploited to develop effective antiosteoporosis agents. PMID: 29683099 [PubMed - as supplied by publisher]
Conclusion Despite the limited significance to differentiate pMN from sMN, sPLA2-IB was correlated with the level of proteinuria in MN patients suggesting to be a potential biomarker for monitoring disease severity and therapeutic effects of both pMN and sMN.
Publication date: Available online 24 April 2018 Source:Methods Author(s): Bin Wu, Jingshan Huang, Lihua Zhang, Mohan Vamsi Kasukurthi, Fangwan Huang, Jiang Bian, Keisuke Fukuo, Tsutomu Kazumi Prior research has indicated that as an important biomarker of chronic low-grade inflammation, high-sensitivity C-reactive protein (hs-CRP) can play important roles on the onset of metabolic syndrome and cardiovascular diseases (CVD). We conducted an integrative approach, which combines biological wet-lab experiments, statistical analysis, and semantics-oriented bioinformatics & computational analysis, to investigate the associa...