Negative influence of preoperative tinnitus on hearing preservation in vestibular schwannoma surgery.

CONCLUSIONS: Microsurgery represents the first therapeutic option for small growing VS with SUH. Our data confirm that key-hole RS removal of VS with intraoperative LS-CE-Chirp ABR monitoring allows good rate of SUH preservation, especially maximum diameter does not exceed 2cm. Preoperative tinnitus seems to indicate a lower hearing reserve and predicts a lower likelihood of HP. PMID: 28945052 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgical Sciences - Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research

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DIABETES type 2 symptoms are triggered when there are problems with blood sugar levels. This is because of problems with the hormone insulin, which affects cells ’ ability to take in sugar. It is possible to develop ‘borderline’ diabetes, or pre diabetes, before the condition. Watch out for these symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: October 2018Source: Biomedicine &Pharmacotherapy, Volume 106Author(s): Rui Xin, Xuhong Sun, Ziying Wang, Wendan Yuan, Weidong Jiang, Lin Wang, Yanxiao Xiang, Hongqin Zhang, Xiaoyan Li, Yun Hou, Wangnan Sun, Pengchao DuAbstractAimsIn this animal study, we tried to test the hypothesis that apocynin could play an anti-inflammation role by inhibiting NLRP3/X-linked inhibitor of apoptosis protein (XIAP) signalling and have an effect on antifibrosis in rats with diabetic nephropathy.Main methodsDiabetic nephropathy rats were induced by tail-vein injection of streptozotocin at 60 mg/kg body weight in sodiu...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Conclusion: Overall, the results of this study suggested the potential beneficial effects of the extract mixture for use as complementary medicine alongside conventional treatment of metformin. The extract mixture contained many highly potent compounds for treating T2DM and preventing short- and long-term risk complications of diabetes.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Substantial data during the last three decades has focused on lipid intervention for the prevention and treatment of atherosclerosis and, more importantly, on the primary and secondary prevention of major cardiovascular disease (CVD) events, including coronary heart disease (CHD) and stroke [1]. Certainly, the majority of the attention during recent decades has been directed at lowering the levels of low-density lipoprotein cholesterol (LDL-C), although some studies have also directed attention at lowering levels of triglycerides (TGs) and/or raising levels of the cardio-protective high-density lipoprotein cholesterol (HDL-C).
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
We read with great interest the paper by Moretti et al. [1] published in IJC in April 1, 2018. They included 107 remote ischemic preconditioning (RIPC) treated patients with coronary artery disease (CAD) [stable 50, acute coronary syndrome (ACS) 57] and 116 sham controls (stable 62, ACS 54) undergoing percutaneous coronary intervention (PCI). Based on the subgroup analysis of diabetes status, they arbitrarily concluded that the contrast-induced nephropathy (CIN) prevention by RIPC may be more pronounced in the non-diabetes group than in diabetes group.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the Editor Source Type: research
In this study, the number of circulating endothelial progenitor cells (EPC) is lower in naïve pulmonary artery hypertension (PAH) patients, and treatment of PAH-tar geted drugs increased EPC levels in the blood of PAH patients. However, there is no elevation of circulating EPC in chronic thromboembolic pulmonary hypertension patients.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the editor Source Type: research
Atrial fibrillation is a common cause of stroke, and diabetes increases stroke risk. Stroke risk may vary depending on the type of diabetes. We investigated whether type 1 and type 2 diabetes are associated with different risks of thromboembolism among patients with atrial fibrillation.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
This study aimed to assess rate of LDL-cholesterol target attainment among patients with diabetes at very-high cardiovascular risk treated with statins, and to identify predictive factors of non-attainment of target in this population.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
This study enrolled 1875 subjects with normal glucose tolerance (age range: 20–78 years). VFA was assessed with magnetic resonance imaging.ResultsThe study population consisted of 1573 subjects without a FHD, 115 subjects with a paternal FHD, and 187 subjects with a maternal FHD. For both genders, VFA was greater in offspring with a maternal FHD compared with those without a FHD (both P 
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Publication date: Available online 21 July 2018Source: Journal of Molecular BiologyAuthor(s): Michela Miani, Bernat Elvira, Esteban N. GurzovAbstractDiabetes is a metabolic disorder affecting more than 400 million individuals and their families worldwide. The major forms of diabetes (type 1 and 2) are characterized by pancreatic β-cell dysfunction and, in some cases, loss of β-cell mass causing hyperglycemia due to absolute or relative insulin deficiency. The BCL-2 homology 3 (BH3)-only protein BIM has a wide role in apoptosis induction in cells. In this review, we describe the apoptotic mechanisms mediated by BI...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
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