Atrichia with Papular Lesions: Importance of Histology at an Early Disease Stage

We report the case of a 5-year-old girl born from consanguineous parents, presenting with alopecia universalis since the age of 8 months, without papules or cysts over the scalp or body. The goal of this paper is to emphasize the relevance of histopathology for the early diagnosis of atrichia with papular lesions in children with alopecia universalis, in settings where genetic testing may not be available.Skin Appendage Disord 2018;4:129-130
Source: Skin Appendage Disorders - Category: Dermatology Source Type: research

Related Links:

We report the case of a patient with longstanding alopecia universalis and severe atopic dermatitis who presented with diffuse induration and mottled dyspigmentation of his scalp. Multiple scalp biopsies revealed diffuse interfollicular fibroinflammation and IgG4 plasma cells with induction of distinctive dedifferentiated follicles not seen in alopecia areata. This complex case may provide insight into the role of specific subsets of T cells not only in respect to the fibroinflammation linked to IgG4-related diseases but also the capacity to modify disease, follicular stem cell activation, immune privilege, cytotoxicity in...
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research
Vineet DubeInternational Journal of Trichology 2021 13(6):32-33 An emerging treatment modality whose established efficacy in systemic inflammatory diseases is now being actively explored for cutaneous disorders: tofacitinib, an oral Janus kinase inhibitor, is one such treatment. Alopecia universalis has been reported to improve with the use of tofacitinib in various case reports and case series. Nail dystrophy is a diverse skin disorder that has been linked to autoimmune illnesses such as psoriasis and psoriatic arthritis in certain subtypes. Alopecia areata and alopecia universalis are also commonly associated with nail ...
Source: International Journal of Trichology - Category: Dermatology Authors: Source Type: research
CONCLUSION: Gender and time since the onset of AA appear to be important variables that must be considered when conducting future studies and interventions with this population. These future studies and interventions should address the informational support needs of people living with AA.PMID:34792929
Source: Puerto Rico Health Sciences Journal - Category: International Medicine & Public Health Authors: Source Type: research
Hair regrowth with no adverse effects following nonablative 2940-nm Er:YAG laser treatment in alopecia universalis patient resulted in high patient satisfaction and compliance. As the main challenge in alopecia universalis is maintenance of regrown hair, patient compliance associated with this treatment might represent an advantage over traditional treatment modalities. AbstractHair regrowth with no adverse effects following nonablative 2940-nm Er:YAG laser treatment in alopecia universalis patient resulted in high patient satisfaction and compliance. As the main challenge in alopecia universalis is maintenance of regrown ...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
Conditions:   Alopecia Areata;   Alopecia Totalis;   Alopecia Universalis;   Alopecia Areata (& Ophiasis);   Alopecia Barbae;   Alopecia Diffuse;   Autoimmune Diseases;   Autoimmune Hyperthyroidism;   Autoimmune Hypothyroidism;   Diabetes Mellitus, Type 1;   Ulcerative Colitis;   Inflammatory Bowel Diseases;   Crohn Disease;   Rheumatoid Arthritis;   Down Syndrome;   Atopic Dermatitis;   Atopic Asthma;   Atopic Rhinitis; ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Alopecia | Alopecia Universalis | Children | Dermatology | Genetics | Girls | Skin