Age-related changes in biochemical bone profile in thalassemic children

This study was conducted with the objective to compare bone turnover mar kers (BTMs) in thalassemic children at different ages.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research

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In conclusion, reducing miR-451a expression levels could enhance bone formation during the progression of osteoporosis, which might be at least partly via the meditation of Bmp6 expression.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Source: Clinical Interventions in Aging - Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Conclusion: Several health maintenance aspects are inadequately addressed by GIs and PCPs, in part because of conflicting perceptions of responsibility. Clear guidelines and better GI/PCP communication are required to ensure effective health maintenance for patients with IBD. PMID: 31528131 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research
Conclusion: A significant proportion of this large cohort of south Indian healthy rural postmenopausal women had osteoporosis at either site with advancing age. Most of them had a suboptimal DCI, and over half of them had VDD.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Task Force Source Type: research
In conclusion, we found osteoblastogenesis was reduced in an acidic environment, and ASIC2, ASIC3, and ASIC4 were most highly expressed in turn during osteoblastogenesis within acidic media. ASIC2 was the most abundantly expressed gene in human bone cells in OVF compared with the control. ASIC2 could be crucial in the pathogenesis of osteoporosis and could serve as a therapeutic target for antiosteoporotic therapies. PMID: 31531354 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
A new ultrasound technique could help clinicians assess bone health and distinguish...Read more on AuntMinnie.comRelated Reading: AAOS: QCT finds low bone density in lumbar fusion patients 3D DEXA enhances hip fracture risk prediction Ultrasound equal to DEXA for assessing bone health USPSTF reaffirms osteoporosis screening USPSTF to review osteoporosis screening
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Setting aside the mice genetically engineered to destroy senescent cells, the combination of dasatinib and quercetin is the oldest of the senolytic treatments used in animal studies. Senolytic therapies are those that selectively destroy senescent cells in old tissues in order to produce rejuvenation, turning back the progression of numerous age-related conditions. Unusually for early stage research, these initial senolytics are actually quite effective, considered in the grand scheme of things. Thus they have moved directly to human trials in some cases. The first data on their ability to produce the same outcomes in huma...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Publication date: Available online 17 September 2019Source: Enzyme and Microbial TechnologyAuthor(s): Yuping Shen, Man Wang, Jinwei Zhou, Yufei Chen, Lili Xu, Mengru Wu, Guohua Xia, James P. Tam, Jiangnan Yu, Xiying Teng, Huan Yang, Xiaobin JiaABSTRACTBaohuoside I, a rare secondary glycoside from Epimedii Folium, has anti-osteoporosis and other pharmacological effects. In addition, it exhibits improved bioactivities compared with its original glycoside icariin. Conventional methods for the production of baohuoside I, such as acid hydrolysis, exhibit very low efficiency with serious pollution and substantial byproducts. The...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
Conditions:   Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Obesity;   Body Weight;   Bone Diseases, Metabolic;   Fractures, Bone;   Osteoporotic Fractures;   Osteoporosis;   Quality of Life;   Fall;   Musculoskeletal Diseases Intervention:   Sponsors:   Suzanne Morin;   CHU de Quebec-Universite Laval Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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