Pfizer helps pump $103M into startup to develop new cancer therapies

A New York startup has been spun-out of Pfizer to develop clinical-stage experimental therapies. Nascent medicine company SpringWorks Therapeutics completed a $103 million series A round led by the New York-based pharma giant with the help of Bain Capital, OrbiMed and LifeArc (formerly known as MRC Technology). Pfizer (NYSE: PFE) granted SpringWorks the rights to help develop four drugs or t herapies that treat various conditions, including post-traumatic stress disorder and cancer. Another New…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news

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The deadly truth about cancer in the fire service will be front and center September 15 as fire fighters and paramedics from across the United States and Canada join grieving families at the IAFF Fallen Fire Fighter Memorial in Colorado Springs, Colorado, to honor those who have lost their lives in the line of duty.   The names of 271 fire fighters who have died in the line of duty from trauma or occupational illness will be etched on to the granite Wall of Honor. The risk of traumatic death in the fire scene has declined over the years – in large part due to the International Association of Fire Fighters’...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Tags: News Administration and Leadership Source Type: news
More research is done on the therapeutic benefits of dogs than on cats and other animals. But there are signs of change.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Animal Behavior Service Dogs and Other Animals Cats Therapy and Rehabilitation Post-Traumatic Stress Disorder Autism Mental Health and Disorders Cancer Breast Cancer Source Type: news
OBJECTIVES: Blood stasis is an important pathophysiologic concept in Traditional East Asian Medicine. It has been considered to be a pathogenic factor in chronic and incurable conditions such as pain, infertility, cancer, coronary heart disease, and others...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Conditions:   Colorectal Cancer;   Bladder Cancer;   Prostate Cancer;   Kidney Cancer;   Advanced Sarcoma Interventions:   Other: Memory structuring intervention + Vagal breathing;   Other: support and attention (usual care) Sponsors:   Centre Oscar Lambret;   SCALab UMR CNRS 9193 Université de Lille Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
RESULTS: The nine studies included were reviewed under two titles as descriptive and qualitative. Based on the results of six descriptive studies, it was determined that the majority of these studies focused on violence and abuse in childhood; depression i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Psychological distress has been indicated to affect the risk of death from cardiovascular disease, cancer, and external causes. Mortality from these major causes of death is also known to be elevated after widowhood when distress is at a heightened level. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Astronauts and cosmonauts have been reported to be at substantially lower age-specific risk of death from chronic disease (primarily heart disease and cancers) in comparison to the general populations of the United States and Russia, respectively. Yet, bot...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
ConclusionAlthough this population of women has above average knowledge scores, they still demonstrated a desire for more information on reproduction after cancer therapy. While PedsQL scores fell within a normal range, survivors report infertility would cause negative emotions.Implication for cancer survivorsThis information can be used refine educational programs within survivorship clinics to improve knowledge of post-treatment reproductive health.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
BOSTON (CBS) – Many people diagnosed with cancer suffer from post-traumatic stress disorder or PTSD. Researchers in Malaysia looked at almost 500 adults who had been diagnosed with different types of cancer. One in five had developed PTSD within a few months of their diagnosis and some of those still had symptoms four years later. Getting the news that you have cancer can be shocking and the treatment itself can be traumatic. And then some patients continue to live in fear that the cancer will return. Patients with PTSD can have sleep problems, may be more likely to use substances, and may avoid seeking treatment fo...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Healthwatch Local News Syndicated Local Cancer Dr. Mallika Marshall PTSD Source Type: news
In this study we demonstrate the use of clustered regularly interspaced short palindromic repeats (CRISPR)-based epigenome editing to alter cell response to inflammatory environments by repressing inflammatory cytokine cell receptors, specifically TNFR1 and IL1R1. This has applications for many inflammatory-driven diseases. It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation." In chronic back pain, for example, slipped or herniated discs are a result of damaged tissue when inflammation causes cells to create ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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