The carolactam strategy is ineffective: Synthesis and biological evaluation of carolactam

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02060K, PaperAndreas Kirschning, Thomas Schmidt, Jonas Ammermann, Irene Wagner-Dobler, Michael Reck, Meike Stiesch, Nico Stumpp, Marly Dalton, Jannik Donner Carolacton, a secondary metabolite isolated from the extracts of Sorangium cellulosum, causes membrane damage and cell death in biofilms of the caries- and endocarditis-associated bacterium Streptococcus mutans and Streptococcus pneumoniae.... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research