Effects of insulin analogs as an add-on to metformin on cutaneous microcirculation in type 2 diabetic patients

Conclusions A strategy of improving glycemic control for 4weeks with insulin analogs improves microcirculatory endothelial reactivity and reduces endothelial biomarkers at fasting, whatever the insulin regimen used. Insulin therapy associated to metformin is able to improve fasting microvascular endothelial function even before complete metabolic control.
Source: Microvascular Research - Category: Biochemistry Source Type: research