Prevalence, transmission, and genetic diversity of blood parasites infecting tundra-nesting geese in Alaska

Canadian Journal of Zoology, e-First Articles. A total of 842 blood samples collected from five species of tundra-nesting geese in Alaska was screened for haemosporidian parasites using molecular techniques. Parasites of the genera Leucocytozoon Danilewsky, 1890, Haemoproteus Kruse, 1890, and Plasmodium Marchiafava and Celli, 1885 were detected in 169 (20%), 3 (
Source: Canadian Journal of Zoology - Category: Zoology Tags: article Source Type: research

Related Links:

In this study, we generated a model to test available formulations based on the P. vivax MSP119 antigen. The Plasmodium berghei strains ANKA and NK65 were modified to express PvMSP119 instead of the endogenous PbMSP119. The hybrid parasites were used to challenge C57BL/6 or BALB/c mice immunized with PvMSP119-based vaccine formulations. The PvMSP119 was correctly expressed in the P. berghei hybrid mutant lines as confirmed by immunofluorescence using anti-PvMSP119 monoclonal antibodies and by Western blot. Replacement of the PbMSP119 by the PvMSP119 had no impact on asexual growth in vivo. High titers of specific antibodie...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionsFour subtypes (STs) of Blastocystis in human was identified in our study and subtype 3 was the most prevalent subtype. The common subtype (ST3) in this study was identical to the reports from other regions of Iran. For identification of the more subtypes of Blastocystis, comprehensive molecular studies with a large number of Blastocystis isolates are suggested.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
ConclusionsThe first study of its kind in Australia found T. gondii infection to be highly prevalent. Toxoplasma gondii infection has been neglected in Australian notifiable disease programs therefore Australian public health authorities should focus on improving education to raise awareness and commence longitudinal epidemiological data collection to supplement public health models targeting T. gondii transmission control.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
(eLife) Malaria parasites can sense a molecule produced by approaching immune cells and then use it to protect themselves from destruction, according to new findings published today in eLife.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Contributors : Carlos Cordon-Obras ; Anna Barcons-Simon ; Christine Scheidig-Benatar ; Aurelie Cla ës ; Florent Dingli ; Damarys Loew ; Artur ScherfSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Plasmodium falciparumHeterochromatin is essential in all eukaryotic systems to maintain genome integrity, long-term gene repression and to help chromosome segregation during mitosis. However, heterochromatin regions must be isolated to avoid its spreading over actively transcribed loci. Such function is accomplished by chromatin boundaries, DNA elements that block heterochromatin self-...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Plasmodium falciparum Source Type: research
Gold nanoparticles (GNPs) are one of the most widely used nanomaterials in various fields. Especially, the unique chemical and physical properties make them as the promising candidates in drug target identific...
Source: Journal of Nanobiotechnology - Category: Nanotechnology Authors: Tags: Research Source Type: research
In malaria, rosetting is described as a phenomenon where an infected erythrocyte (IRBC) is attached to uninfected erythrocytes (URBC). In some studies, rosetting has been associated with malaria pathogenesis. Here, we have identified a new type of rosetting. Using a step-by-step approach, we identified IGFBP7, a protein secreted by monocytes in response to parasite stimulation, as a rosette-stimulator forPlasmodium falciparum- andP. vivax-IRBC. IGFBP7-mediated rosette-stimulation was rapid yet reversible. Unlike type I rosetting that involves direct interaction of rosetting ligands on IRBC and receptors on URBC, The IGFBP7...
Source: eLife - Category: Biomedical Science Tags: Immunology and Inflammation Microbiology and Infectious Disease Source Type: research
Infection by the parasite Toxoplasma, which affects about 33% of world population, is associated with an increased risk of several mental health disorders, the most strongly with schizophrenia. It is unknown whether schizophrenia is associated with this infection the most strongly, or whether this association has just been the most intensively studied for historical reasons. We used the data from 6,367 subjects tested for toxoplasmosis who took part in an internet survey to search for associations of these infections with 24 mental health disorders and evidence of otherwise impaired mental health. The typical symptom assoc...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
mans Roelants A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have remained mostly unexplored. Previous studies of microhylids found no evidence of peptide secretion, suggesting that this defence adaptation was evolutionarily lost. We conducted transcriptome analyses of the skins of Phrynomantis bifasciatus and Phrynomantis microps, two African microhylid species long suspected to be poisonous. Our analyses reveal 17 evo...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
an Bishop In this era of precision medicine, insights into the resistance mechanism of drugs are integral for the development of potent therapeutics. Here, we sought to understand the contribution of four point mutations (N51I, C59R, S108N, and I164L) within the active site of the malaria parasite enzyme dihydrofolate reductase (DHFR) towards the resistance of the antimalarial drug pyrimethamine. Homology modeling was used to obtain full-length models of wild type (WT) and mutant DHFR. Molecular docking was employed to dock pyrimethamine onto the generated structures. Subsequent all-atom molecular dynamics (MD) simulat...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
More News: Genetics | Parasitic Diseases | Parasitology | Zoology