Inflammation in response to phytohemagglutinin injection in the Talas tuco-tuco (Ctenomys talarum): implications for the estimation of immunocompetence in natural populations of wild rodents

Canadian Journal of Zoology, e-First Articles. The immunological variation in wild populations and its relation to life-history traits has recently become a central topic in the field of evolutionary biology, considering the critical contribution of immunity to an individual’s fitness. A common technique used by ecologists to estimate immunocompetence in wild populations is the phytohemagglutinin (PHA) – skin test. In this test, the degree of local swelling triggered by PHA is usually considered an estimate of T-lymphocyte activity, although there is an ongoing debate regarding this interpretation. Here, we coupled the PHA–skin test with a histological analysis to examine the temporal development of the cell-mediated response in the subterranean rodent Talas tuco-tuco (Ctenomys talarum Thomas, 1898). The inflammation response involved lymphocytes, neutrophils, eosinophils, and macrophages at the site of injection, achieving an increase of total leukocytes from 12 to 48 h after injection. However, the abundance of any of the leukocytes observed did not correlate with the degree of swelling at any time studied, suggesting that caution should be taken when interpreting the results of the PHA-induced swelling response. Particularly, the magnitude of macroscopic swelling should not be considered a priori as indicative of T-lymphocyte activity in wild-caught rodents. Our results highlight the importance of avoiding oversimplified approaches to measuring immu...
Source: Canadian Journal of Zoology - Category: Zoology Tags: article Source Type: research

Related Links:

Conclusions: Patients showing a clinical benefit during 6 cisplatin-doublet chemotherapy cycles may have a sustained survival benefit from single-maintenance chemotherapy. PMID: 32098457 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research
Conclusions: CLDN18 plays a role in the pathogenesis of asthma and NAC diminishes airway inflammation and responsiveness by modulating CLDN18 expression. PMID: 32098455 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research
AbstractTexting is increasingly used by teachers to communicate with families about classroom logistics and to support learning at home. The authors review the research evidence supporting texting as a tool for increasing family members ’ engagement and their children’s learning, including the authors’ own evidence‐based texting program, Text to Talk, which targets students’ vocabulary development. Finally, the authors offer guidelines to teachers regarding effective texting practices to maximize student learning and fami ly engagement. These guidelines might prove useful to teachers beginning to ...
Source: Reading Teacher - Category: Child Development Authors: Tags: Feature Article Source Type: research
AbstractUnderresourced communities often have limited access to print and materials to promote children's early literacy development. Recognizing that the neighborhood is a unit of social change, organizations that engage families in early reading and learning with their children, therefore, have increasingly become part of the community landscape. Recently, efforts to promote early literacy have found families in a less conventional place: the local laundromat. The authors report on a study of six laundromats in low ‐income communities, three of which were transformed to include literacy‐related play centers and three...
Source: Reading Teacher - Category: Child Development Authors: Tags: Feature Article Source Type: research
AbstractWith increasing expectations on students regarding written communication, the promotion of student agency in writing is more important now than ever. Teachers must find ways to engage and empower all learners throughout the writing process so they can produce authentic and meaningful writing independently. To promote such agency, educators must allow students to do more of the work, even while scaffolding for students who need more support. Supporting students in ways that promote metacognition, using their own voice and ideas, pinpointing their individual needs, and encouraging student leadership throughout the wr...
Source: Reading Teacher - Category: Child Development Authors: Tags: Teaching Tip Source Type: research
AbstractClassroom libraries are an important component of elementary classrooms. These collections support readers ’ literate identities, their motivation to read, and their access to texts that reflect a world outside of the classroom. Yet, many classrooms lack texts that mirror the racial, cultural, and linguistic diversity of students and their lived experiences. The authors—three elementary teachers (gra des 1–3) and three teacher educators—inventoried the hundreds of books in the teachers’ classrooms. The team discovered that the libraries lacked diversity across intersectional representa...
Source: Reading Teacher - Category: Child Development Authors: Tags: Feature Article Source Type: research
AbstractA group of words, labeled the core vocabulary, can be expected to be prominent across all texts. Scholarship made possible by digital databases of words and new analytic systems has shown that approximately 2,500 morphological families account for most of the words in texts —an average of 91.5% of all words in the Common Core State Standards exemplars from kindergarten through College and Career Ready. The rare vocabulary of texts is so extensive and varied that, without a foundation in the core vocabulary, students are likely to struggle with the meanings of rare wo rds. Words are in the core vocabulary beca...
Source: Reading Teacher - Category: Child Development Authors: Tags: Article Source Type: research
AbstractVoices From the Classroom essays share readers ’ reflections on teaching experiences, advice for new teachers, and perspectives on current issues.
Source: Reading Teacher - Category: Child Development Authors: Tags: Voices From The Classroom Source Type: research
AbstractVoices From the Classroom essays share readers ’ reflections on teaching experiences, advice for new teachers, and perspectives on current issues.
Source: Reading Teacher - Category: Child Development Authors: Tags: Voices From The Classroom Source Type: research
AbstractSupporting young students ’ oral language development is vital in ensuring their future success as readers. One important way that early childhood teachers can foster language development is by having extended conversations with students. The authors share research about the importance of rich teacher–student conversatio ns and explain how less verbal students may miss out on conversational opportunities. The authors also explain how to create conditions in the classroom that are supportive of students’ engagement and talk, then give specific strategies for encouraging extended conversations.
Source: Reading Teacher - Category: Child Development Authors: Tags: Feature Article Source Type: research
More News: Allergy & Immunology | Biology | Skin | Zoology