What Would Graham-Cassidy Do To Transplant Patients?

People with kidney or organ transplants are an overlooked group at grave risk under Graham-Cassidy.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

Related Links:

We present the case of a 65-year-old immunocompromised male with a history of kidney transplantation, diabetes, coronary artery bypass, and cardiac resynchronization therapy device implantation who was finally diagnosed with an unusual form of infective endocarditis due to co-infection of fungal and bacterial pathogens. He was afebrile at the time of admission and presented with decompensated heart failure and pneumonia. A spleen abscess was discovered incidentally and prompted us to search for a cardiac source of emboli. Culture of the suppurative fluid drained percutaneously from the abscess was positive for Enterococcus...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
SUMMARY The aim of this study is to discuss the global costs attributed to chronic kidney disease (CKD) and its impact on healthcare systems of developing countries, such as Brazil. This is a systematic review based on data from PubMed/Medline, using the key words “ costs ” and “ chronic kidney disease ” , in January 2017. The search was also done in other databases, such as Scielo and Google Scholar, aiming to identify regional studies related to this subject, published in journal not indexed in PubMed. Only papers published from 2012 on were included. Studies on CKD costs and treatment modalities ...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
CONCLUSION: There is a lack of information in literature regarding renal involvement in PNH, albeit it is possible to state that the pathophysiological mechanisms of acute and chronic impairment differ. Despite not being a curative therapy, Eculizumab is able to ease kidney lesions in these patients.RESUMO INTRODU ÇÃO: A hemoglobinúria paroxística noturna (HPN) é uma doença genética adquirida, caracterizada por hemólise mediada pelo sistema complemento, eventos trombóticos e citopenias variáveis. Envolvimento renal pode ocorrer, contribuindo com morbidad...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
(ERA-EDTA) The EKHA project 'Improving Organ Donation and Transplantation in the EU' will be launched on the European Commission's Health Policy Platform in 2019, an interactive tool to boost discussions about public health concerns and to share knowledge and best practices. Thus, transplantation, especially kidney transplantation and the lack of organs in the EU, will be in the focus of European healthcare discussions in 2019.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Therapeutic plasma exchange (TPE) is an important therapy for recurrent focal segmental glomerulosclerosis (rFSGS) post kidney transplant. suPAR has been causally implicated in rFSGS, and shown to be a unique ...
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
Abstract Hepatitis C direct acting antiviral (DAA) therapy has evolved so that infected patients with advanced chronic kidney disease (CKD) can now anticipate the opportunity for sustained virologic response equivalent to that of the broader population of patients with hepatitis C. This has revolutionized the field of transplantation as it relates to renal transplant candidates with hepatitis C and the use of grafts from hepatitis C virus (HCV) viremic donors. In treating this population of patients, special consideration must be given to the timing of anti-viral therapy and drug-drug interactions. Herein we revie...
Source: Seminars in Dialysis - Category: Urology & Nephrology Authors: Tags: Semin Dial Source Type: research
Cardiovascular disease is a significant cause of morbidity and mortality in patients with end-stage renal disease (ESRD) and kidney transplant (KT) patients. Compared with left ventricular (LV) ejection fracti...
Source: Journal of Cardiovascular Magnetic Resonance - Category: Radiology Authors: Tags: Research Source Type: research
Authors: Masola V, Bellin G, Vischini G, Dall'Olmo L, Granata S, Gambaro G, Lupo A, Onisto M, Zaza G Abstract Renal ischemia/reperfusion (I/R) injury occurs in patients undergoing renal transplantation and with acute kidney injury and is responsible for the development of chronic allograft dysfunction as characterized by parenchymal alteration and fibrosis. Heparanase (HPSE), an endoglycosidase that regulates EMT and macrophage polarization, is an active player in the biological response triggered by ischemia/reperfusion (I/R) injury. I/R was induced in vivo by clamping left renal artery for 30 min in wt C57BL/6J m...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Martínez Calderón P, Cruz Martínez R, Parmentier de León C, Grimaldo Rico OE, Castelán Carmona N, Madrigal Bustamante JA, Rodríguez Covarrubias F, Gabilondo Pliego B, Morales Buenrostro LE, Alberú J, Contreras AG, Vilatobá M PMID: 30541672 [PubMed - as supplied by publisher]
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
Imagine being a pediatric kidney transplant patient and having to miss school or extracurricular activities because of clinic appointments and routine blood tests. Now imagine being offered a take-home kit that has everything you and your caregivers need to collect a blood sample at home that can be shipped to a lab. For patients like 14-year-old Josh Knapp, a kidney transplant patient in England, that choice became a reality, thanks to an initiative at Nottingham University Hospital designed to facilitate easier therapeutic drug monitoring of tacrolimus and creatinine. Made specifically for pediatric transplant patients, ...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news
More News: Kidney Transplant | Kidney Transplantation | Pharmaceuticals | Transplant Surgery | Transplants | Urology & Nephrology