Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence.

CONCLUSIONS: High Nrf2 expression in alveolar macrophages and type II pneumocytes was significantly associated with the decreased recurrence risk and was the independent factor predicting a better incidence-of-recurrence in PSP. Our results suggest that Nrf2 activation in high risk patients may be a potential target for reducing PSP recurrence. PMID: 28932556 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/28932556?dopt=Abstract

Source: Journal of Thoracic Disease - September 23, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

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