Medical News Today: Too much manganese may lead to fatal heart infection

New research finds that excessive intake of manganese, an essential nutrient in leafy vegetables, may lead to a Staphylococcus aureus heart infection.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Related Links:

Authors: Bassetti M, Del Puente F, Magnasco L, Giacobbe DR Abstract Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is among the most frequent causative agents of acute bacterial skin and skin-structure infections (ABSSSI) and has been associated with increased risks of invasive disease and of treatment failure.Areas covered: In this review, we focus on those novel anti-MRSA agents currently in phase I or II of clinical development that may enrich the armamentarium against ABSSSI caused by MRSA in the future.Expert opinion: Promising agents belonging to either old or novel antibiotic classes are cu...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
This study will be a useful tool for analyzing the pharmacokinetics of DAP. PMID: 32238639 [PubMed - in process]
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research
ConclusionsIn hospitalized adults with MRSA BSI, CT with any BL was independently associated with improved clinical outcomes and may ultimately be selected as preferred therapy.
Source: Infectious Diseases and Therapy - Category: Infectious Diseases Source Type: research
PMID: 32237117 [PubMed - in process]
Source: Angewandte Chemie - Category: Chemistry Authors: Tags: Angew Chem Int Ed Engl Source Type: research
Publication date: June 2020Source: Molecular Immunology, Volume 122Author(s): Arshad Zahoor, Yaping Yang, Chao Yang, Sher Bahadar Khan, Christine Reix, Farhan Anwar, Meng-yao Guo, Ganzhen Deng
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
While immunoglobulin (Ig) E is a prominent biomarker for early-onset, its levels are often elevated in non-allergic late-onset asthma. However, the pattern of IgE expression in the latter is mostly polyclonal, with specific IgEs low or below detection level albeit with an increased total IgE. In late-onset severe asthma patients, specific IgE to Staphylococcal enterotoxins (se-IgE) can frequently be detected in serum, and has been associated with asthma, with severe asthma defined by hospitalisations, oral steroid use and decrease in lung function. Recently, se-IgE was demonstrated to even predict the development into seve...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: State of the Art Source Type: research
vanZ, a member of the VanA glycopeptide resistance gene cluster, confers resistance to lipoglycopeptide antibiotics independent of cell wall precursor modification by the vanHAX genes. Orthologs of vanZ are present in the genomes of many clinically relevant bacteria, including Enterococcus faecium and Streptococcus pneumoniae; however, vanZ genes are absent in Staphylococcus aureus. Here, we show that the expression of enterococcal vanZ paralogs in S. aureus increases the minimal inhibitory concentrations of lipoglycopeptide antibiotics teicoplanin, dalbavancin, oritavancin and new teicoplanin pseudoaglycone derivatives. T...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Purpose of review Mass gathering events bring people from across all continents increasing the risk of spread of aerosol transmissible respiratory tract infections. Respiratory tract infections for instance in pilgrims attending the world's largest recurring annual pilgrimage, the Hajj are common. We review recent literature on viral and bacterial infectious diseases with special focus on the Hajj. Recent findings The prevalence of bacterial and viral infections continue to increase, because of the acquisition of rhinovirus, coronaviruses (229E, HKU1, OC43), influenza A H1N1, Streptococcus pneumoniae, Haemophilus infl...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla Source Type: research
A bundled intervention aimed at improving basic preventive measures significantly reduces surgical-site infections and Staphylococcus aureus transmission in the perioperative period, a randomized clinical trial shows.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: General Surgery News Source Type: news
Authors: Soriano A, Rossolini GM, Pea F Abstract Introduction: Acute bacterial skin and skin-structure infections (ABSSSI) are a subgroup of skin and soft tissue infections and are a common source of morbidity in both the community and the hospital setting. The most common cause of ABSSSI is Staphylococcus aureus, which also includes methicillin-resistant S. aureus (MRSA), together with beta-hemolytic streptococci, enterococci, and Gram-negative bacteria. Since the emergence of MRSA, the management of ABSSSI has become more challenging. Novel therapies alternative to teicoplanin and vancomycin, intravenous agents c...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
More News: Cardiology | Diets | Health | Heart | Manganese | Nutrition | Staphylococcus Aureus | Vegetables