GSE93325 Proteogenomic characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling
Contributors : Jiheon Shin ; Minhyung Kim ; Hee-Jung Jung ; Hye L Cha ; Haeyoung Suh-Kim ; Sanghyun Ahn ; Jaehoon Jung ; YounAh Kim ; Yukyung Jun ; Sanghyuk Lee ; Daehee Hwang ; Jaesang KimSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC).Here, we present an integrated analysis of transcriptomes and proteomes generated from wild-type and TSC1/Emx1-Cre forebrains.This led to comprehensive lists of genes and proteins whose expression levels were altered by hyperactivated mTOR signaling.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research