Consolidative radiotherapy following autologous stem cell transplant for relapsed or refractory diffuse large B-cell lymphoma.

Conclusions The use of consolidative radiotherapy following high-dose chemotherapy and autologous stem cell transplantation for the treatment of relapsed or refractory DLBCL appears to significantly improve LRC. For patients with masses ≥2 cm following transplant there was also an improved 2-year PFS and OS. Prospective trials are needed to further identify the patients who would derive the most benefit from consolidative radiotherapy in the transplant setting.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research