Trends in standardized mortality among individuals with schizophrenia, 1993-2012: a population-based, repeated cross-sectional study.

We examined mortality time trends and premature mortality among individuals with and without schizophrenia over a 20-year period. METHODS: In this population-based, repeated cross-sectional study, we identified all individual deaths that occurred in Ontario between 1993 and 2012 in persons aged 15 and over. We plotted overall and cause-specific age- and sex-standardized mortality rates (ASMRs), stratified all-cause ASMR trends by sociodemographic characteristics, and analyzed premature mortality using years of potential life lost. Additionally, we calculated mortality rate ratios (MRRs) using negative binomial regression with adjustment for age, sex, income, rurality and year of death. RESULTS: We identified 31 349 deaths among persons with schizophrenia, and 1 589 902 deaths among those without schizophrenia. Mortality rates among people with schizophrenia were 3 times higher than among those without schizophrenia (adjusted MRR 3.12, 95% confidence interval 3.06-3.17). All-cause ASMRs in both groups declined in parallel over the study period, by about 35%, and were higher for men, for those with low income and for rural dwellers. The absolute ASMR difference also declined throughout the study period (from 16.15 to 10.49 deaths per 1000 persons). Cause-specific ASMRs were greater among those with schizophrenia, with circulatory conditions accounting for most deaths between 1993 and 2012, whereas neoplasms became the leading cause of death for those without schizophr...
Source: cmaj - Category: General Medicine Authors: Tags: CMAJ Source Type: research

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Source: Cell Reports - Category: Cytology Source Type: research
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Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research
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Source: JAMA Specialty Journals Author Interviews - Category: General Medicine Source Type: podcasts
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Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior General Inside Schizophrenia Mental Health and Wellness Motivation and Inspiration Psychology avolition Lack Of Motivation Living With Schizophrenia Source Type: blogs
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Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
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Source: JAMA Psychiatry - Category: Psychiatry Source Type: research
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Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
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