Structural Characteristics of the Brain Reward Circuit Regions in Patients with Bipolar I Disorder: A Voxel-based Morphometric Study

Bipolar I disorder (BD-I) is often misdiagnosed, leading to inadequate treatment and significant disability along with reduced quality of life. Recent neural models suggest that the reward circuitry is affected in bipolar disorder. The purpose of the present study was to identify structural abnormalities in the brain reward-processing neural circuitry among patients with BD-I. 21 patients with BD-I and 21 healthy controls (HC) participated in this study. Structural magnetic resonance imaging was performed.

Source: Psychiatry Research: Neuroimaging - September 20, 2017 Category: Psychiatry Authors: Junyong Lee, Sunyoung Choi, June Kang, Eunsoo Won, Woo-Suk Tae, Min-Soo Lee, Byung-Joo Ham Source Type: research