The impact of lymph node dissection and positive lymph nodes on cancer specific mortality in contemporary pT2 ‐3 non‐metastatic renal cell carcinoma treated with radical nephrectomy

ConclusionIn contemporary and historical patients LND or its extent, do not protect from CSM. However, the NPN increases the rate of CSM in pT3 patients. In consequence, LND and its extent appear to have little or any therapeutic value in pT2‐3NanyM0 patients, besides its prognostic impact. High risk non‐metastatic patients may represent a target population for a multi‐institutional prospective trial.This article is protected by copyright. All rights reserved.

Source: BJU International - September 20, 2017 Category: Urology & Nephrology Authors: Michele Marchioni, Marco Bandini, Raisa S. Pompe, Tristan Martel, Zhe Tian, Shahrokh F. Shariat, Anil Kapoor, Luca Cindolo, Alberto Briganti, Luigi Schips, Umberto Capitanio, Pierre I. Karakiewicz Tags: Original Article Source Type: research