Log in to search using one of your social media accounts:


Faulty cell signaling derails cerebral cortex development, could it lead to autism?

(University of North Carolina Health Care) As the embryonic brain develops, a complex cascade of cellular events occur, starting with progenitors -- the originating cells that generate neurons and spur proper cortex development. If this cascade malfunctions then the brain can develop abnormally. Eva Anton's lab at UNC has shown how the deletion of the protein APC in progenitor leads to massive disruption of brain development and the Wnt protein pathway, which previously was linked to genes associated with autism.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

Related Links:

A digital healthcare startup is using an artificial intelligence (AI) platform to help aid in the detection of autism. Palo Alto, CA -based Cognoa said FDA has classified the algorithm-powered solution as a Class II diagnostic medical device. The FDA designation gives the company a path to get full clearance as a medical diagnostic for autism. “The goal actually is this summer to submit to the FDA to get full clearance under a de novo as a medical diagnostic,” Sharief Taraman, vice president of medical at Cognoa, told MD+DI. “I think we should be able to get that at the end of the year or by 201...
Source: MDDI - Category: Medical Devices Authors: Tags: Medical Device Business Digital Health Source Type: news
Two extremely upsetting statistics came out not too long ago. Reports have found that not only is there a link between absenteeism in school and mental illness, but there is also a correlation between suspensions from schools and children who have mental or neurological health concerns. These include personality disorders, depression, ADHD, autism and spectrum disorders, and other mental health issues, both treated and untreated. This is a major concern. Rather than recognizing symptoms and reaching out to provide support to the students who need it most, those children are being thrown out of the very environment that wou...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: ADHD and ADD Caregivers Children and Teens Parenting Personal Personality Research Stigma Stress Student Therapist Students Success & Achievement Suicide Coping Skills defiant oppositional Discipline Emotional Disabilities Source Type: blogs
Authors: Azer SA, Bokhari RA, AlSaleh GS, Alabdulaaly MM, Ateeq KI, Guerrero APS, Azer S Abstract The aims of this study were to determine the following: first, are there educationally useful videos of parents of children with autism sharing their experiences? Second, do any of the data related to videos help in identifying useful videos? And third, what do posted comments tell us? YouTube was searched for videos of parents sharing their experiences. The following parameters were collected: title, creator, URL, duration, number of viewers, likes, dislikes, comments, days on YouTube, and country. Based on agreed-upo...
Source: Informatics for Health and Social Care - Category: Information Technology Tags: Inform Health Soc Care Source Type: research
A highly critical review of the care at Mendip House for people with autism provided by the National Autistic Society
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Rachel C. Leung, Elizabeth W. Pang, Evdokia Anagnostou, Margot J. Taylor
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Increasing evidence links the microbiome's composition with several psychiatric and neurological diseases, including autism, schizophrenia, attention deficit hyperactivity disorder, Parkinson's disease, Alzheimer's disease and multiple sclerosis – Mark Greener investigates.
Source: Progress in Neurology and Psychiatry - Category: Neurology Authors: Tags: News review Source Type: research
ConclusionsSporadic clinical studies reported improved behavioral symptoms in children with autism following PIO treatment. We show that PIO can aid in normalization of the E/I balance in the primary somatosensory cortex, a potential physiological mechanism underlying the positive effects of PIO treatment.
Source: Molecular Autism - Category: Molecular Biology Source Type: research
AbstractBackgroundNeurofibromatosis 1 (NF1) is a monogenic model for syndromic autism. Statins rescue the social and cognitive phenotype in animal knockout models, but translational trials with subjects>  8 years using cognition/behaviour outcomes have shown mixed results. This trial breaks new ground by studying statin effects for the first time in younger children with NF1 and co-morbid autism and by using multiparametric imaging outcomes.MethodsA single-site triple-blind RCT of simvastatin vs. placebo was done. Assessment (baseline and 12-week endpoint) included peripheral MAPK assay, awake magnetic reson...
Source: Molecular Autism - Category: Molecular Biology Source Type: research
In conclusion, the two versions of the Portuguese version of the W-ADL Scale (15 items and 17 items) demonstrated the acceptable validity and reliability measurement to evaluate ADL for adolescents and adults with developmental disabilities. However, the 15-item version seems to be the best option for Portuguese language speakers.
Source: Sport Sciences for Health - Category: Sports Medicine Source Type: research
Publication date: Available online 21 February 2018 Source:Developmental Cognitive Neuroscience Author(s): Themelis Karaminis, Louise Neil, Catherine Manning, Marco Turi, Chiara Fiorentini, David Burr, Elizabeth Pellicano Ensemble perception, the ability to assess automatically the summary of large amounts of information presented in visual scenes, is available early in typical development. This ability might be compromised in autistic children, who are thought to present limitations in maintaining summary statistics representations for the recent history of sensory input. Here we examined ensemble perception of facial em...
Source: Developmental Cognitive Neuroscience - Category: Neuroscience Source Type: research
More News: Autism | Brain | Genetics | Health Management | International Medicine & Public Health | Neurology