Usefulness of 99mTc-pyrophosphate Scintigraphy in Screening of Cardiac Transthyretin Amyloidosis in Patients with Heart Failure Over Sixty Years of Age

Background: Cardiac transthyretin amyloidosis (ATTR) might be one of major causes of heart failure especially in elderly patients. However, it appears underdiagnosed because of a relatively high threshold of performing endomyocardial biopsy in daily practice. The purpose of the present study was to evaluate the usefulness of 99mTc- pyrophosphate (PYP) scintigraphy in screening of ATTR. Methods: Consecutive patients with non-ischemic and non-valvular heart failure over sixty years of age studied with 99mTc-PYP scintigraphy were analyzed.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research