Ganglioglioma progression to combined anaplastic ganglioglioma and anaplastic pleomorphic xanthoastrocytoma. Case report and literature review

Composite ganglioma and pleomorphic xanthoastrocytoma with anaplastic features in both components is an extremely rare glioneuronal tumor. 5 cases of anaplastic progression in the glioma component have been reported. These tumors generally affect young patients who suffer brain tumor-related epilepsy, are usually located in the temporal lobe or in the cerebellum, and may associate leptomeningeal spreading. Its current optimal treatment consists of maximal safe surgical resection and adjuvant chemoradiotherapy.
Source: World Neurosurgery - Category: Neurosurgery Authors: Tags: Case Report Source Type: research