Patterns of botulinum toxin treatment for spasticity and bleeding complications in patients with thrombotic risk.

Patterns of botulinum toxin treatment for spasticity and bleeding complications in patients with thrombotic risk.
Toxicon. 2017 Sep 15;138:188-190
Authors: Phadke CP, Thanikachalam V, Ismail F, Boulias C
Abstract
The purpose of this study was to assess the prevalence of compartment syndrome or major bleeding episodes and compare compartment syndrome, patient and intervention characteristics in 110 patients with stroke (treated with Warfarin, new oral anticoagulants, antiplatelet, or no anticoagulants) treated for spasticity in deep leg compartment muscles with botulinum toxin injections [onabotulinumtoxinA (n = 77); incobotulinumtoxinA (n = 33)]. We reviewed 674 injection cycles (range 1-25 cycles per patient) and found no cases of compartment syndrome in any patient groups.
PMID: 28919457 [PubMed - as supplied by publisher]

Source: Toxicon - September 15, 2017 Category: Toxicology Authors: Phadke CP, Thanikachalam V, Ismail F, Boulias C Tags: Toxicon Source Type: research