Bone Marrow WT1 Levels in Allogeneic Hematopoietic Stem Cell Transplant (HCT) for Acute Myeloid Leukemia and Myelodysplasia: Clinically Relevant Time-Points and 100 Copies Threshold Value

• WT1 levels in bone marrow before and after HCT provide relevant prognostic information. WT1 levels at leukocyte recovery may be helpful to plan therapeutic strategies. Sustained bone marrow WT1 levels below 100 copies are associated with a favorable outcome.

Source: Biology of Blood and Marrow Transplantation - September 19, 2017 Category: Hematology Authors: Josep F. Nomded éu, Albert Esquirol, Maite Carricondo, Marta Pratcorona, Montserrat Hoyos, Ana Garrido, Miguel Rubio, Elena Bussaglia, Irene García-Cadenas, Camino Estivill, Salut Brunet, Rodrigo Martino, Jorge Sierra Source Type: research