Salvage rates and prognostic factors after relapse in children and adolescents with malignant peripheral nerve sheath tumors

ConclusionsOur study confirmed the unsatisfactory prognosis for pediatric patients with relapsing MPNST and pointed to a risk‐adapted stratification model for the purposes of deciding second‐line treatments. For the time being, an aggressive surgical approach seems to be the only effective salvage treatment and should be recommended. New therapeutic approaches are under evaluation with a view to improving current outcomes.

Source: Pediatric Blood and Cancer - September 19, 2017 Category: Cancer & Oncology Authors: Luca Bergamaschi, Gianni Bisogno, Carla Manzitti, Paolo D'Angelo, Giuseppe Maria Milano, Angela Scagnellato, Mirko Cappelletti, Stefano Chiaravalli, Patrizia Dall'Igna, Rita Alaggio, Antonio Ruggiero, Martina Di Martino, Maria Carmen Affinita, Marta Piero Tags: RESEARCH ARTICLE Source Type: research