Autoimmune disease variants regulate GSDMB gene expression in human immune cells and whole blood [Biological Sciences]

There are four gasdermin (GSDM) proteins, including GSDMA, GSDMB, GSDMC, and GSDMD, in the human genome (1). Genome-wide association studies have reported genetic variants at 17q12.2.1 loci, including GSDMA, GSDMB, and ORDML3 genes, to be associated with kinds of autoimmune diseases, including asthma, type 1 diabetes, inflammatory bowel disease (IBD),...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Letters Source Type: research