Poster 62: Effect on Voluntary Movements of Simultaneous Upper and Lower Limb AbobotulinumtoxinA Injections in Conjunction with Guided Self-Rehabilitation Contracts in Adults with Spastic Hemiparesis: Methodology of the ENGAGE Study
Jean-Michel Gracies: Consulting fees or other remuneration (payment) - Merz, Allergan, Ipsen; Research Grants - Allergan, Ipsen, Merz; Consulting - Merz
Infants in homes with frequent cleaning product use have increased odds for childhood wheeze, asthma
Condition: Healthy Volunteers Interventions: Drug: AV-1; Drug: Placebo Sponsors: AbViro LLC; National Institute of Allergy and Infectious Diseases (NIAID) Recruiting
Publication date: Available online 17 February 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): James H. Clark, Fuad M. Baroody, Robert M. NaclerioAbstractSinonasal disease in its multiple forms affects billions of people worldwide. Although physicians train to precisely diagnose a patient and then treat appropriately, the sheer number of people afflicted with sinonasal disease precludes this approach. We argue that patients should first be treated with an intranasal corticosteroid for 2 weeks. Based on their perceived response, they should be triaged. Those who respond well can be instruct...
Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there is a need for biomarkers which allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on micro-arrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed which may discriminate two of the most common forms of asthma, ...
In our recent report we studied associations between early-life exposure to individual bacterial genera of the indoor microbiota and the development of asthma.1 In a correspondence to this report, Fu et al2 compliment our novel approach, but question some of the statistical choices made and ask for a new sensitivity analysis.
Increasing evidence indicates that the development of asthma is associated with microbial communities in indoor environments.1,2 However, because of high temporal and spatial variations and the multidimensionality of microbiome data set, it is challenging to identify an accurate set of protective and risk microbes for asthma. The current standard is performing association analysis between asthma and microbial community composition or quantity of cellular components (eg, endotoxins or microbial volatile organic compounds).
Chronic rhinosinusitis (CRS) is a common medical problem, frequently seen by those in primary care, allergy, and otolaryngology. Our understanding of chronic sinusitis is continuously evolving, with some recent substantial advancements in the knowledge of the pathophysiology of CRS and new treatment options. For example, there is a greater understanding of how the environment, through allergic rhinitis, air pollution, and the patient ’s own microbiome, may play a role in the development of CRS. The recognition of CRS as an inflammatory disease state has been further refined, but trying to define the disease in terms ...
New evidence suggests the Zoster Vaccine Live — administered to prevent shingles — could also reduce the risk of stroke in older adults.Medscape Medical News
Condition: Allergy Intervention: Diagnostic Test: advanced glycation endproducts reader Sponsor: Federico II University Recruiting
Conditions: HIV Infections; LTBI Interventions: Drug: Dolutegravir (DTG); Drug: Isoniazid (INH); Drug: Rifapentine (RPT); Drug: Antiretroviral Therapy (ART); Dietary Supplement: Pyridoxine (Vitamin B6) Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); ViiV Healthcare (VH) Not yet recruiting