Poster 68: Urinary Symptoms and Urinalysis do not Predict Uropathogens on Pyrosequencing in Patients with Spinal Cord Injury

Emma Nally: I Have No Relevant Financial Relationships To Disclose
Source: PM and R - Category: Rehabilitation Authors: Source Type: research

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Monosynaptic rabies tracing can be used to map inputs to stem cell ‐derived neurons grafted to models of neurodegenerative disease and injury. These studies indicate that graft neurons receive anatomically‐appropriate inputs, but it remains to be determined whether those inputs are necessary for functional recovery. Next‐generation rabies tracing is poised to address this outstanding question, which may aid ongoing translational efforts. ABSTRACTFetal neural progenitor grafts have been evaluated in preclinical animal models of spinal cord injury and Parkinson's disease for decades, but the initial reliance on primary...
Source: Stem Cells - Category: Stem Cells Authors: Tags: Translational and Clinical Research Source Type: research
In conclusion, the cPAM induces an effective treatment of SCI by the lesion tissue specific delivery of the prodrug polymer via its robust scar binding effect, making the scar tissue a drug releasing platform for sustained treatment of SCI.
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
This study aimed to investigate the association between traumatic spinal cord injury (TSCI) and the risk of affective and other psychiatric disorders, and the role of the rehabilitation therapies. METHODS: In this population-based, retr...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Conclusions: Our review reported some potential substances that may improve neurological outcome in acute SCI: MP, vitamin D associated with progesterone, and erythropoietin. Their potential benefits were modest in the evaluated studies, requiring further randomized clinical trials with large samples of patients, without statistical artifacts, for routine clinical use. Furthermore, potential adverse effects must be considered with the use of neuroprotective agents in SCI. Until then, the use of these substances may be experimental or restricted to specific clinical situations.
Source: Journal of Spinal Disorders and Techniques - Category: Surgery Tags: Systematic Review Source Type: research
Publication date: Available online 25 February 2020Source: NeuroImage: ClinicalAuthor(s): Michela Azzarito, Maryam Seif, Sreenath Kyathanahally, Armin Curt, Patrick Freund
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
CONCLUSIONS: Increase of miR-34a suppresses neuronal apoptosis and alleviates microglia inflammation by negatively targeting the Notch pathway, thereby improving neural recovery and locomotor function. PMID: 32096191 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Spinal Cord, Published online: 26 February 2020; doi:10.1038/s41393-020-0444-4Outpatient and community care for preventing pressure injuries in spinal cord injury. A qualitative study of service users’ and providers’ experience
Source: Spinal Cord - Category: Research Authors: Source Type: research
CONCLUSION: NMDA receptor antagonists, especially amantadine, may ameliorate SCI by inducing angiogenesis, affecting inflammation and apoptosis. It inhibits oxidative stress and the signaling pathways following SCI in rats. PMID: 32091112 [PubMed - in process]
Source: Turkish Neurosurgery - Category: Neurosurgery Authors: Tags: Turk Neurosurg Source Type: research
The American Congress of Rehabilitation Medicine (ACRM) offers an opportunity for members to be the guest editor of a Supplement to its journal, the Archives of Physical Medicine and Rehabilitation (Archives). The goal of the ACRM supplements is to publish high quality scientific manuscripts, which are thematically organized and of interest to ACRM members and to the general readership of the Archives. We are interested in proposals in all fields of rehabilitation, but especially those of interest to the ACRM membership as indicated by the existence of special interest and networking groups for brain injury, spinal cord in...
Source: Archives of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Organization news Source Type: research
The recruitment of immune system cells into the central nervous system (CNS) has a profound effect on the outcomes of injury and disease. Glia-derived chemoattractants, including chemokines, play a pivotal rol...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
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