Abstract P274: Double Hit! A Unique Case of Resistant Hypertension [Session Title: Onsite Poster Competition II]

Discussion: Evidence shows that a hyperfunctioning parathyroid gland may contribute to maintaining hyperaldosteronism in PA. This is based on in-vitro studies showing PTH increased aldosterone secretion from adrenocortical cells in a concentration dependent manner. Gene expression and immunohistochemistry studies show PTH receptors in aldosterone-producing adenomas and MR receptors in parathyroid cells, suggesting a bi-directional relationship. The significance of this case is in the potential for further understanding of the pathophysiology of common causes of secondary hypertension.
Source: Hypertension - Category: Cardiology Authors: Tags: Poster Abstract Presentations Source Type: research