Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA < sub > 3 < /sub > Receptor Subtype and is Increased in Obesity

Conclusion: LPA is able to interrupt insulin signaling in primary rat hepatocytes via the LPA3 receptor subtype. Moreover, the bioactive lipid LPA (16: 0) is increased in obesity.Cell Physiol Biochem 2017;43:445 –456
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research