Diabetes in Disaster Mode: One Town's Tale of Evolving Relief Needs
We're all hearing the news about the historic devastation dealt to the Gulf Coast and southeastern states as well as the Caribbean islands by Hurricanes Harvey and Irma -- and a new dose of catastrophe may be heading toward the East Coast now. Fo...
New research finds that girls with autoimmune hypothyroidism show reduced brown adipose tissue activation in response to cold stimulation.Journal of the Endocrine Society
Is single gland excision a viable option for the treatment of MEN1-associated primary hyperparathyroidism? How does it compare with other treatment methods?Clinical Endocrinology
TYPE 2 diabetes is a common condition yet many people in the UK will not realise they have it because the symptoms do not necessarily make you feel unwell. Symptoms are caused by consistently high blood sugar levels, and, overtime, this can affect different parts of the body, including the shoulder.
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Women whose periods stop before the age of 40 are at greater risk of diabetes, heart disease, strokes, asthma and breast cancer, the study found. The UK menopause average is 51.
Publication date: Available online 18 January 2020Source: Toxicology ReportsAuthor(s): Afaf M. Weli, Hanady S. Al-Saadi, Rouqaya S. Al-Fudhaili, Amzad Hossain, Zabida Binti Putit, Mahmood K. JasimAbstractMedicinal plant as herbal medicine is widely used to cure infectious diseases. Rubus fruticosus L (R. fruticosus) has been studied for its antimicrobial and cytotoxic activities. Different polarity leave extracts were prepared by using hexane, chloroform, ethyl acetate and hydro alcoholic solvents. Agar diffusion method has been used to assess the antibacterial activity against two gram-positive Enterococcus faecalis and S...
ConclusionThe present study revealed that oral administration of CM extract for 28 days, at dosage up to 1000 mg/kg did not induce toxicological damage in rats. From acute toxicity study, the median lethal dose (LD50) of the extract was estimated to be more than 5000 mg/kg.Graphical abstract
This study is a 48-week, one-center (only Kanazawa University Hospital), open-label, randomized, parallel trial. Patients who satisfied the eligibility criteria were randomly assigned (1:1) to receive once-daily 20 mg tofogliflozin or 0.5 mg glimepiride. The sample size was calculated to be 14 in each group with a significance level of 0.05 and power of 0.90. The design required 40 evaluable patients in this study. The primary endpoint of this study will be the improvement in liver histology between liver b iopsies at baseline and after 48 weeks of treatment. The secondary efficacy endpoints in the present ...