Human Papillomavirus Vaccination Uptake in Canada: A Systematic Review and Meta ‑analysis

The objectives of this study are twofold and aim to (1) determine the levels and (2) examine the various factors in fluencing vaccine uptake among the general Canadian population. A literature search was conducted on seven databases, followed by screening, methodological quality review (using modifed Newcastle‑Ottawa Scale), and data extraction. Pooled meta‑analysis and a subgroup analysis were conducted str atifying by a number of variables (age, sex, type of program, and method of payment) determinedapriori. A total of 718 peer ‑reviewed articles were initially identifed with 12 remaining after screening and underwent methodological quality review. HPV vaccination uptake in Canada varied from 12.40% (95% confdence interval [CI] 6.77–20.26) to 88.20% (95% CI 85.72–90.39). The pooled random effects model showed the HPV vaccination uptake to be 55.92% (95% CI 44.87–66.65). The subgroup analysis showed that vaccination uptake was 66.95% (95% CI 55.00–77.89) in participants≤ 18 years as compared to 13.58% (95% CI10.93–16.46) in participants> 18 years. Uptake for females was higher 57.23% (95% CI: 45.40– 68.66) when compared to that of 47.01% (95% CI: 0.82–97.75) in males. HPV vaccine uptake among school ‑based programs was 69.62% (95% CI 57.27–80.68) as compared to 18.66% (95% CI 6.66–34.92) for community ‑based programs. Vaccination uptake for publicly funded programs was signifcantly higher 66.95% (95% CI 5...
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research