A case of unruptured aneurysm of the internal carotid artery presenting as olfactory hallucinations.

CONCLUSION: According to our knowledge, previous reports are limited to cases of large middle cerebral artery aneurysms compressing the lateral orbitofrontal cortex, and this is apparently the first report of a case where olfactory hallucinations occurred from direct stimulation of the entorhinal cortex by an internal carotid and posterior communicating artery bifurcation aneurysm. We examined the pathophysiology underlying the development of olfactory hallucinations. We found craniotomy clipping and focal resection to be useful from the standpoint of seizure control. Whether seizure control can also be obtained with intracranial aneurysm coiling should be investigated in the future. PMID: 28904824 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

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ConclusionsThe resolution of the CE-MRV in the present study met the requirement for detection of small conflicting vessels during SEEG planning. The visualized venous landmarks could be used for visual guidance to the surgical zone. As a non-invasive approach, CE-MRV is practical to use in the clinical setting.
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
We describe a 6-year-old child with refractory focal motor seizures symptomatic to a neuroepithelial dysembryoblastic tumor in the left temporo-parietal region. He underwent limited resection of the lesion in order to avoid sequelae in his language function. A functional study at age of 17 years revealed an overlap of Wernicke's area with the tumor and areas of incipient language reorganization in the contralateral hemisphere. An invasive neuromodulation procedure was designed to enhance neuroplasticity. After craniotomy, he underwent language training and simultaneous electrical inhibition of language using an electrode g...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Direct electrical cortical stimulation (CS) is used for mapping of eloquent cortex in patients with refractory focal epilepsy undergoing intracranial electroencephalography (icEEG) as part of their presurgical evaluation. CS can be performed with subdural grids, strips and depth electrodes (or combinations of these) after craniotomy or with stereotactically-inserted depth electrodes (stereo electroencephalography, SEEG)[1,2]. CS remains the gold standard for functional mapping of language, motor and sensory areas in relation to the epileptogenic zone (EZ) prior to epilepsy surgery[1,2].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
This study is designed to explore the effect and feasibility of SNB with ropivacaine for postoperative analgesia in pediatric patients undergoing craniotomy. Further aims are to compare the effects of preoperative and postoperative SNB on postoperative analgesia in order to identify whether there is a preemptive analgesic effect and determine the better time to implement SNB in pediatric patients during craniotomy.Trial registrationChinese Clinical Trial RegistryChiCTR1800017386. Registered on 27 July 2018.
Source: Trials - Category: Research Source Type: clinical trials
Publication date: September 2020Source: Interdisciplinary Neurosurgery, Volume 21Author(s): Thomas Wychowski, A. James Fessler, Jacob Nadler, Nimish Mohile, Benjamin H. Brinkmann, Gregory A. Worrell, Kevin Walter, Gretchen L. Birbeck
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
We report the case of a 32-year-old Irish Traveller woman who presented to the emergency department in convulsive status epilepticus with abnormal neuroimaging features characteristic of LCC. Her medical history consisted of epilepsy, intellectual impairment, previous craniotomies for excision of cerebral cysts and resection of a tibial osteogenic sarcoma. Whole exome sequencing identified a previously described homozygous variant, NR_033294.1 n.*5C>G, in the 3 ′ UTR of theSNORD118 gene. Her sister was subsequently found to be homozygous for the same variant but with a significantly milder clinical phenotype consi...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
ConclusionsOur classification of gliomas involving  motor-related eloquent areas was useful for predicting postoperative motor functional prognosis in patients who underwent motor mapping with DCS. Even if no positive sites were detected, a conservative strategy of tumor resection is recommended in cases that gliomas located close to the posterior limb of the internal capsule.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: There is limited, low-certainly evidence to suggest that AED treatment administered prophylactically is either effective or not effective in the prevention of postcraniotomy (early or late) seizures. The current evidence base is limited due to the different methodologies employed in the trials and inconsistencies in the reporting of outcomes including deaths and adverse events. Further evidence from good-quality, contemporary trials is required in order to assess the clinical effectiveness of prophylactic AED treatment compared to placebo or no treatment, or other AEDs in preventing postcraniotomy seizures in ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
A craniotomy is required to access the brain for tumor resection or epilepsy treatment, and despite precautionary measures, infectious complications occur at a frequency of 1 –3%. Approximately half of cranioto...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
Abstract We developed a junior-real-time neuropsychological testing (j-RTNT) and used it during surgery of a right fronto-insular dysembryoplastic neuroepithelial tumor causing seizures in a 16 years old female. The j-RTNT included tasks from the battery NEPSY-II. Pre-surgery evaluation detected a below average performance in visuo-spatial planning, inhibition, visual attention, planning and borderline performance in speeded naming. The j-RTNT allows detecting sudden decreases that could be caused by resection. During surgery, ECoG was characterized by slow sharp activity and spikes on the electrodes explorin...
Source: Brain and Cognition - Category: Neurology Authors: Tags: Brain Cogn Source Type: research
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