Mismatch negativity impairment is associated with deficits in identifying real-world environmental sounds in schizophrenia

Patients with schizophrenia (SZ) have impairments in processing auditory information that have been linked to deficits in cognitive and psychosocial functioning. Dysfunction in auditory sensory processing in SZ has been indexed by mismatch negativity (MMN), an event-related potential evoked by a rare, deviant stimulus embedded within a sequence of identical standard stimuli. Although MMN deficits in SZ have been studied extensively, relatively little is known about how these deficits relate to accurately identifying real-world, ecologically-salient sounds.

Source: Schizophrenia Research - September 16, 2017 Category: Psychiatry Authors: Yash B. Joshi, Barbara Breitenstein, Melissa Tarasenko, Michael L. Thomas, Wei-Li Chang, Joyce Sprock, Richard F. Sharp, Gregory A. Light Source Type: research