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For Irritating Itch, a Promising Option Under Scrutiny For Irritating Itch, a Promising Option Under Scrutiny

Investigational serlopitant afforded clinical trial patients quick relief for a variety of pruritis-characterized diseases.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Dermatology News Source Type: news

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AbstractPurpose of ReviewStudies show frequent usage but low adherence rates and poor satisfaction from topical therapy for psoriasis. These were attributed to low efficacy, inconvenience of application, and poor cosmetic quality for different body parts.Recent FindingsMulticenter surveys on patients suggest a two-way holistic approach, where patients convey what bothers them most and doctors explain how products address specific concerns. New rapid response targeted topical agents, in cosmetically acceptable preparations, applied less often, are undergoing efficacy and safety studies, ideally on large populations up to 1 ...
Source: Current Dermatology Reports - Category: Dermatology Source Type: research
Authors: Heratizadeh A, Werfel T, Gieler U, Kupfer J, Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene (ARNE) Abstract Atopic dermatitis (AD) represents a chronic inflammatory skin disease showing a 1-year prevalence of 2-3% during adulthood. In a national randomized, controlled multicenter study initiated by the "Arbeitsgemeinschaft Neurodermitisschulung im Erwachsenenalter" (ARNE, Working Group on Educational Training for Adults with Atopic Dermatitis) a program for structured patient education conducted by a multiprofessional team was developed and evaluated. At 1â...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
The substance P/neurokinin 1 receptor (NK1R) pathway is critical in chronic pruritus; anecdotal evidence suggests antagonism of this pathway can reduce chronic itch.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
HEAD lice are a normal part of life and there is nothing to be embarrassed, worried or ashamed about. While you may think you have tried every trick in the book to get rid of the infestation, there are several reasons why still be causing you and your child to itch and scratch. Here ’s how to get rid of them for good.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Itch is defined as an unpleasant sensation that evokes a desire to scratch. Recently, a surprising diversity of the sensory and spinal cord dorsal horn neurons that specifically process pruritic stimuli has been discovered. Despite this knowledge, our understandings of supraspinal mechanisms that are engaged in the itch processing are largely unknown. Here we took an unbiased approach using immediate early gene (cFos) mapping for precise dissection of brain circuits that mediate itch processing.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
ECZEMA cream could help to treat the skin condition. But, this mother claims she cured her baby ’s dry, itchy skin by using this moisturiser that’s available for under £5 a tube.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
WEDNESDAY, Feb. 14, 2018 -- Asthma and allergies can put on damper on your Valentine's Day romancing, an expert warns. " Keeping everyone free of allergy and asthma flare-ups helps keep the focus on romance this Valentine's Day. Red or itchy eyes,...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Summary Atopic dermatitis is a skin disease, commonly known as eczema. It affects up to 1 in 10 adults. Atopic dermatitis is usually very itchy, causing people to wake up at night, and feel “low”. This state of general discomfort is known as reduced quality of life. Dupilumab is a new treatment approved in the U.S.A. for adults with moderate‐to‐severe atopic dermatitis. The treatment blocks some of the mechanisms involved in the disease. In a clinical trial conducted in Europe, researchers observed 109 patients with moderate‐to‐severe atopic dermatitis. The patients received dupilumab over 12 weeks...
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Plain Language Summary Source Type: research
ConclusionOverall, toxicity of anti‐CD20 monoclonal antibodies was limited to post‐infusion side‐effects in children with more complex disease. The relatively safe profile of anti‐CD20 antibodies support their use as steroid‐sparing agents in children with INS.
Source: British Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Authors: Tags: DRUG SAFETY Source Type: research
The Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel is expressed in nociceptors where, when activated by chemical or thermal stimuli, it functions as an important transducer of painful and itch-related stimuli. Although the interaction of TRPV1 with proteins that regulate its function has been previously explored, their modulation by...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: PNAS Plus Source Type: research
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