Parkinson's: Sniff test could predict risk up to a decade earlier

New study suggests that a test of olfaction could determine a person's risk of developing Parkinson's disease up to 10 years before a diagnosis.
Source: Parkinson's Disease News From Medical News Today - Category: Neurology Tags: Parkinson's Disease Source Type: news

Related Links:

AbstractBackgroundThe differential diagnosis of Parkinson ’s disease (PD) and multiple system atrophy (MSA) remains a challenge, especially in the early stage. Here, we assessed the value of transcranial sonography (TCS) to discriminate non-tremor dominant (non-TD) PD from MSA with predominant parkinsonism (MSA-P).MethodsEighty-six MSA-P patients and 147 age and gender-matched non-TD PD patients who had appropriate temporal acoustic bone windows were included in this study. All the patients were followed up for at least 2  years to confirm the initial diagnosis. Patients with at least one substantia nigra (SN) e...
Source: Translational Neurodegeneration - Category: Neurology Source Type: research
Publication date: Available online 21 July 2018Source: NeuropsychologiaAuthor(s): Nancy Stirnimann, Karim N'Diaye, Florence Le Jeune, Jean-François Houvenaghel, Gabriel Robert, Sophie Drapier, Dominique Drapier, Didier Grandjean, Marc Vérin, Julie PéronAbstractThe possible hemispheric specialization of the basal ganglia during emotional prosody (i.e., vocal emotion) processing has still to be elucidated. Coupled with affective measures and neuroimaging, Parkinson's disease offers a unique opportunity to study this question, on account of its characteristically asymmetric striatal dysfunction, which tra...
Source: Neuropsychologia - Category: Neurology Source Type: research
Condition:   Parkinson Disease Interventions:   Drug: Ganoderma;   Drug: Placebos Sponsor:   Xuanwu Hospital, Beijing Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The most common drug for treating Parkinson's disease can have potentially disabling side effects. Researchers believe these could be relieved by ketamine.
Source: Parkinson's Disease News From Medical News Today - Category: Neurology Tags: Parkinson's Disease Source Type: news
The most common drug for treating Parkinson's disease can have potentially disabling side effects. Researchers believe these could be relieved by ketamine.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Parkinson's Disease Source Type: news
In conclusion, we focus on the various newer molecular mechanisms that are associated with the basic understanding of neuroinflammation in neurodegeneration.
Source: Neurochemistry International - Category: Neuroscience Source Type: research
Laura Avanzino, Mirta Fiorio, Antonella Conte
Source: Frontiers in Neurology - Category: Neurology Source Type: research
(Johns Hopkins Medicine) A drug currently in clinical trials for treating symptoms of Parkinson's disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Antonini A, Stoessl AJ, Kleinman LS, Skalicky AM, Marshall TS, Sail KR, Onuk K, Odin PLA Abstract BACKGROUND: Lack of a global consensus on definition of advanced Parkinson disease (APD) and considerations for timing of device-aided therapies may result in heterogeneity in care. OBJECTIVES: To reach consensus among movement disorder specialists regarding key patient characteristics indicating transition to APD and guiding appropriate use of device-aided therapies in the management of PD symptoms. METHODS: A Delphi-panel approach was utilized to synthesize opinions of movement disorder specialists a...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Conclusion: Tensor decomposition is a useful method for the modeling and analysis of multisensor time series in patients with Parkinson's disease. Significance: Tensor-decomposition factors can be potentially used as physiological markers for Parkinson's disease, and effective features for machine learning that can provide early prediction of the disease progression.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
More News: Parkinson's Disease | Study