MicroRNA-137 and its downstream target LSD1 inversely regulate anesthetics-induced neurotoxicity in dorsal root ganglion neurons.

CONCLUSIONS: MiR-137-3p and its downstream target LSD1 are inversely associated to regulate anesthetics-induced neurotoxicity in DRGN. This signaling pathway may be a therapeutic candidate to reduce anesthetics-induced neurological damage in human patients. PMID: 28899795 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28899795?dopt=Abstract

Source: Brain Research Bulletin - September 9, 2017 Category: Neurology Authors: Chen L, Wang X, Huang W, Ying T, Chen M, Cao J, Wang M Tags: Brain Res Bull Source Type: research