Kedrab (Rabies Immune Globulin Solution for Intramuscular Injection) - new on RxList

Source: RxList - New and Updated Drug Monographs - Category: Drugs & Pharmacology Source Type: news

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In conclusion, intravenous neuronal mitochondria-targeted dual-modified novel biomimetic nanosystems are a promising therapeutic candidate for ROS-induced mitochondrial dysfunction in AD. PMID: 32228100 [PubMed - in process]
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
Publication date: Available online 31 March 2020Source: Preventive Veterinary MedicineAuthor(s): Brinkley Raynor, Micaela De la Puente-León, Andrew Johnson, Elvis W. Díaz, Michael Z. Levy, Sergio E. Recuenco, Ricardo Castillo-Neyra
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Publication date: Available online 30 March 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Alan Stokes, Johanne Pion, Ornella Binazon, Benoit Laffont, Maude Bigras, Guillaume Dubois, Karine Blouin, Jamie K. Young, Michael A. Ringenberg, Nawel Ben Abdeljelil, Julius Haruna, Luis-Alexander Rodriguez
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
AbstractRabies is the most critical zoonotic disease in Iran, which imposes many extra costs on health care system in each country. The present study aimed to determine the molecular characteristics of the wild circulating strains of the rabies virus (RABV) collected in Iran during 2015 –2017. Rabies-suspected samples were collected from different regions of Iran and identified for RABV antigen confirmation using fluorescent antibody tests. Polymerase chain reaction (PCR) was performed on positive samples and gene sequencing was done on rabies nucleoprotein and glycoprotein gene s to determine the rabies molecul...
Source: Virus Genes - Category: Genetics & Stem Cells Source Type: research
ira Fooks In South Africa, canid rabies virus (RABV) infection is maintained in domestic and wildlife species. The identification of rabies in African civets raised the question of whether this wildlife carnivore is a potential reservoir host of RABVs of direct and ancestral dog origin (dog-maintained and dog-derived origins) with an independent cycle of transmission. Genetic analyses of African civet nucleoprotein sequences for 23 African civet RABVs and historically published sequences demonstrated that RABVs from African civets have two origins related to dog and mongoose rabies enzootics. The data support observ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
 It’s often said that fear is the most dangerous virus on the planet. While a relatively small percentage of people will contract the new coronavirus, or COVID-19, the fear it provokes will chip away at the mental health of nearly everyone who hears about it. So why does COVID-19 inspire so much fear when there are other diseases lurking in the shadows? And what can we do about it? In today’s podcast, our guest Dr. David Batman, a registered medical practitioner in the U.K., discusses how this high level of unprecedented global panic is being intensified by the non-stop media, and specifically, social media....
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Health-related Interview Podcast The Psych Central Show Source Type: blogs
This study therefore defines the first stem cell-derived ex-vivo model system to study rabies pathogenesis in human neurons. This new model system demonstrates the potential for enabling an increased understanding of molecular mechanisms in human rabies, which could lead to improved control methods.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
In this study we standardized anin vitro assay for determination of residual live virus combining viral isolation techniques with direct immunofluorescence detection and viral quantification by a molecular method. Standardization of viral recovery steps and quantification by RT-qPCR were performed and the combined method was shown to be 3 fold more sensitive than thein vivo assay. It was possible to identify viral suspensions cultures, which still had residual viable rabies virus particles, evidencing the importance to implement this method in quality control schemes of rabies vaccine production. In addition, this develope...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
by Susan Nadin-Davis, Tore Buchanan, Larissa Nituch, Christine Fehlner-Gardiner Despite proactive measures to prevent raccoon rabies entering Canada from the United States, several incursions of this disease have occurred. The largest outbreak, first reported in December 2015 in the city of Hamilton, Ontario, has resulted in the reporting of 449 animal cases as of December 31 , 2018. Initial phylogenetic studies on the index case suggested that this outbreak was not due to local cross-border spread from the Niagara region of the United States where raccoon rabies has persisted for several years. Phylogenetic analysis of w...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
A Utah man who became infected with rabies after handling several bats potentially exposed 279 other people, most of them health workers.
Source: JAMA - Category: General Medicine Source Type: research
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