Health systems in low income countries - four new overviews

Four new Cochrane EPOC  overviews of reviews show reliable evidence on the effects of different ways of organising, financing, and governing health systems in low-income countries and identify important evidence gaps.Links to the new overviews in the Cochrane Library:Delivery arrangments |Financial arrangements |Governance arrangements |Implementation strategiesStrengthening health systems in low-income countries is key to achieving universal health coverage and achieving the health-related Sustainable Development Goals. Achieving these goals requires informed decisions about health systems. Systematic reviews on the effects of different health system arrangements are essential for making informed decisions, and many such reviews are available. However, policymakers and other stakeholders may struggle to identify which reviews are reliable and what are the key results.Broad overviews of the findings of systematic reviews can help policymakers, their support staff, and other stakeholders to identify strategies for addressing problems with how their health systems are organised, financed, and governed and with identifying effective strategies for implementing changes. It can also help to identify needs and priorities for new evaluations of health system arrangements and for systematic reviews.A team ofCochrane researchers from Argentina, Chile, Norway, and South Africa prepared four overviews of the available evidence from up-to-date systematic reviews about the effec...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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Publication date: November 2018Source: Journal of Comparative Pathology, Volume 165Author(s): M.P. Dagleish, J.J. Clark, C. Robson, M. Tucker, R.J. Orton, M.S. RocchiSummaryLouping-ill (LI), caused by louping-ill virus (LIV), results in a frequently fatal encephalitis primarily affecting sheep and red grouse (Lagopus lagopus scotica), but it does occur in other species. An adult male Border collie dog was definitively diagnosed with fatal LI and the lesion profile, LIV antigen distribution and full genome sequence of the LIV responsible were investigated to determine if this differed significantly from sheep-derived LIV. N...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
Authors: Ocampo-Piraquive V, Nieto-Aristizábal I, Cañas CA, Tobón GJ Abstract INTRODUCTION: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by organ damage, flare-remission pattern and increased mortality when compared with the general population. SLE mortality depends on epidemiological, sociodemographic, genetic and clinical factors. Mortality causes have been mainly grouped in disease activity, infections and cardiovascular complications. Lupus nephritis and neuropsychiatric lupus are the main manifestations associated to mortality. Bacterial infection remain...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
Authors: Steben M, Tan Thompson M, Rodier C, Mallette N, Racovitan V, DeAngelis F, Stutz M, Rampakakis E Abstract Publicly funded administration of the quadrivalent HPV (qHPV) vaccine in school-aged girls was implemented for all Canadian provinces and territories between 2007 and 2009. However, the impact of female qHPV vaccination in Canada has yet to be evaluated. This systematic literature review of studies published between September 1, 2006 and September 1, 2016 looked at real-world evidence related to the effects of qHPV vaccination on prevalence of HPV infection and disease in Canada over the past decade. Pu...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
In this report, we propose that the molecular mechanisms of beneficial actions of CR should be classified and discussed according to whether they operate under rich or insufficient energy resource conditions. Future studies of the molecular mechanisms of the beneficial actions of CR should also consider the extent to which the signals/factors involved contribute to the anti-oxidative, anti-inflammatory, anti-tumor and other CR actions in each tissue or organ, and thereby lead to anti-aging and prolongevity. RNA Interference of ATP Synthase Subunits Slows Aging in Nematodes https://www.fightaging.org/archives/...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Rengganis I Abstract Low adult vaccination coverage in Indonesia may contribute to a recent outbreak of diphtheria in Indonesia. Although well known as a pediatric vaccine, diphtheria vaccination should be administered as booster to adolescence and adults for longer prevention. Adult vaccine differs from pediatric vaccine but have similar protection. Additionally, there is special recommendation to vaccinate pregnant women and elderly people aged 65 years or more. PMID: 30333279 [PubMed - in process]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
Authors: Nelwan EJ Abstract Dengue viral infection remains a major public health problem. As many as 400 million people are infected yearly. Even though the vaccine is available, the use of dengue vaccine is still limited due to some concerns. Among patient infected with dengue viral infection, early recognition of the virus and prompt supportive treatment are important to avoid complication and mortality.The clinical spectrum of dengue viral infection is diverse ranging from undifferentiated fever to dengue shock syndrome characterized by plasma leak and hemoconcentration. No specific antiviral therapy is availabl...
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
Authors: Fraile M, Barreiro Alonso E, de la Vega J, Rodríguez M, García-López R, Rodríguez M Abstract INTRODUCTION: Since June 2016, there has been an increase in cases of acute hepatitis A (AHA) in several European countries, mainly affecting men who have sex with men (MSM). The aim was to know the characteristics of AHA diagnosed in recent months, comparing them with a previous series. PATIENTS AND METHODS: All cases of AHA diagnosed in adults between November 2016 and December 2017 (G-I; n=108) were prospectively collected and compared with a series also prospectively collected be...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Publication date: Available online 19 October 2018Source: Pharmacology &TherapeuticsAuthor(s): André Moraes Nicola, Patrícia Albuquerque, Hugo Costa Paes, Larissa Fernandes, Fabricio F. Costa, Erika Seki Kioshima, Ana Karina Rodrigues Abadio, Anamélia Lorenzetti Bocca, Maria Sueli FelipeAbstractThe need for better antifungal therapy is commonly accepted in view of the high mortality rates associated with systemic infections, the low number of available antifungal classes, their associated toxicity and the increasing number of infections caused by strains with natural or acquired resistance. The urg...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Influenza is the leading cause of vaccine-preventable deaths in the United States. Influenza also tops the list of the burden of disease and disability-adjusted life years (DALYs) according to a Eurosurveillance article. The flu is more likely to cause severe illness and harm pregnant women as compared to women who are not pregnant. Changes in the immune system, heart, and lungs during pregnancy make pregnant women (including women up to two weeks following childbirth) more susceptible to severe illness from flu, including illness that directly results in hospitalization. Pregnant women with influenza also have a...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Infectious Disease OB/GYN Source Type: blogs
In conclusion, both vaccine regimens are capable of stimulating specific Th1- biased immune responses and conferring cross protection against B. melitensis and B. abortus infections. Therefore, they could be introduced as new potential candidates for the development of subunit vaccines against Brucella infection.
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
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