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How Weight Loss Can Reverse Type 2 Diabetes

An analysis published in The BMJ aims to let doctors and the public in on a little-known secret: Type 2 diabetes, in many cases, is curable. People can reverse their diabetes by losing about 33 pounds, say the authors of the new paper, despite popular belief that the diagnosis is always a permanent one. If more people were striving for this goal, and if more doctors were documenting instances of diabetes remission, complication rates and health-care costs could both be reduced dramatically, the authors say. The analysis is based on evidence from recent clinical trials. In one from 2011, people who were recently diagnosed with Type 2 diabetes returned their blood sugar levels to normal when they lost weight on a calorie-restrictive diet. In a 2016 follow-up study, people who had been diabetic for up to 10 years were able to reverse their condition when they lost about 33 pounds. Mike Lean, professor of human nutrition at the University of Glasgow in Scotland, is an author of both the new analysis and of those earlier trials. He says a person’s likelihood of remission from diabetes is greatest in the first five years after being diagnosed. Type 2 diabetes, he wrote in an email, is a disease “best avoided by avoiding the weight gain that drives it.” For people who do develop it, he believes that evidence-based weight-loss programs could help them achieve lasting remission. “Not all can do it, but they should all be given the chance with good support,&rd...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized blood sugar calories can you reverse diabetes diabetic diet Heart Disease how to prevent diabetes insulin is diabetes curable metabolism pre-diabetes type 2 diabetes Weight loss Source Type: news

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Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Breast Cancer breast cancer symptoms breast cancer treatment Exercise Meditation Nutrition TIME Health Breast Cancer yoga yoga cancer patients Source Type: news
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The objective of this study was to evaluate the safety and necessity of antiplatelet therapy on patients with Stanford Type B aortic dissection (TBAD) who underwent endovascular aortic repair (EVAR). METHODS: The present study retrospectively analyzed 388 patients with TBAD who underwent EVAR and coronary angiography. The primary outcomes were hemorrhage, death, endoleak, recurrent dissection, myocardial infarction, and cerebral infarction in patients with and without aspirin antiplatelet therapy at 1 month and 12 months. RESULTS: Of those 388 patients, 139 (35.8%) patients were treated with aspirin and 249 (64.2...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
We thank Dr. Kawada for his thoughtful comments in his letter [1] regarding our recent study [2]. Dr. Kawada was concerned about that past smoking history, instead of current smoking associated with coronary heart disease (CHD) in type 2 diabetes (T2D) and speculated that obesity would be a confounding factor on the association. However, based on our study (see Table 3) [2], the results of both univariate and multiple logistic regression analyses revealed that past smoking was associate with CHD in T2D; whereas neither univariate nor multiple logistic regression analysis showed significant association of current smoking with CHD in T2D.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
With all the talk about reverting back to the dietary roots of our species, some may ask: Isn’t this the same as the paleo diet, the popular interpretation of diet prior to agriculture? The Wheat Belly and Undoctored lifestyle and the popular notion of a Paleolithic diet overlap substantially, but there are differences. So let’s discuss the points of difference. First of all, I am not bashing the ideas promoted by followers of the paleo concepts. The ideas they follow are much better than conventional notions of healthy eating, and wonderful results can indeed be achieved on a paleo diet. Many authors from the ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Paleo Diet Undoctored Wheat Belly blood sugar diabetes diy health Dr. Davis grain-free grains low-carb prebiotic resistant starch Wheat Belly Total Health Source Type: blogs
The cardiovascular complications of type 2 diabetes (T2DM) are contributing considerably to morbidity and mortality worldwide, heart failure (HF) being one of the most frequent. The adverse effect of T2DM on myocardium can develop early, and is clinically presenting as left ventricular (LV) diastolic dysfunction in the absence of other heart disease to micro and macrovascular complications leading to severe forms of systolic dysfunction and terminal heart falilure. Therfore, clinical presentation can vary from asymptomatic or mild to severe heart failure symtoms.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
Li et al. evaluated the associations of alcohol consumption, tobacco smoking, hypertension, obesity, depression and sleep duration with coronary heart disease (CHD) development among patients with type 2 diabetes mellitus (T2D) with special reference to the gender differences [1]. By logistic regression analysis, the odds ratios (ORs) (95% confidence intervals (CIs)) of female, older age (>=65), past smoking, long sleep duration, hypertension, and high cholesterol level were 0.51 (0.35-0.74), 1.95 (1.36-2.79), 1.76 (1.22-2.52), 1.7 (1.05-2.77), 3.49 (2.31-5.29) and 1.76 (1.25-2.48), respectively.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
Publication date: Available online 18 September 2017 Source:Journal of Biomedical Informatics Author(s): Wan Li, Lina Zhu, Hao Huang, Yuehan He, Junjie Lv, Weimin Li, Lina Chen, Weiming He Complex chronic diseases are caused by the effects of genetic and environmental factors. Single nucleotide polymorphisms (SNPs), one common type of genetic variations, played vital roles in diseases. We hypothesized that disease risk functional SNPs in coding regions and protein interaction network modules were more likely to contribute to the identification of disease susceptible genes for complex chronic diseases. This could help to f...
Source: Journal of Biomedical Informatics - Category: Information Technology Source Type: research
Type 2 diabetes mellitus (T2DM) is a major risk factor for heart disease. Mortality rates following myocardial infarction (MI) are significantly increased in T2DM patients due to dysfunctional left ventricle (LV). However, molecular pathways underlying accelerated post-MI heart failure (HF) in T2DM remain unclear. We investigated the underlying mechanisms by inducing MI in a well-established model of T2DM and control mice. Cardiac imaging revealed a significantly decreased global LV ejection fraction (EF) in parallel with increased mortality post-MI in T2DM mice compared to controls.
Source: American Journal of Pathology - Category: Pathology Authors: Tags: Regular Article Source Type: research
This study was carried out to determine the effects of flaxseed oil administration on gene expression levels related to insulin, lipid and inflammation in overweight diabetic patients with coronary heart disease (CHD). This randomized double-blind, placebo-controlled trial was conducted among 60 diabetic patients with CHD. Subjects were randomly allocated into two groups to intake either 1000  mg n-3 fatty acid from flaxseed oil containing 400 mg α-Linolenic acid [ALA (18:3n-3)] (n = 30) or placebo (n = 30) twice a day for 12 weeks. Gene expression related to insulin, lipid and infl...
Source: Lipids - Category: Lipidology Source Type: research
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