The Latest: Judge bashes Shkreli's offer for Clinton's hair
A judge who revoked the bail of former pharmaceuticals company CEO Martin Shkreli and had him taken to jail says his offer to pay $5,000 for a Hillary Clinton hair with the follicle was "solicitation of an assault."
ConclusionOur physical science principle analysis proposes that the preferred rehabilitation tendon pathway is to try and decrease tendon stiffness to allow for more tendon lengthening. The body's morphological alterations of the pathological tendon are also consistent with this approach. For mid‐substance Achilles tendinopathy this adaptation of decreased stiffness ultimately increases the tendons ability to withstand applied force during lengthening.This article is protected by copyright. All rights reserved.
Background: Knee replacement typically results in reduced pain and improved function, but it is unclear if these improvements lead to weight loss. Objective: The purpose of this study was to examine weight change patterns preoperatively and postoperatively among overweight/obese knee replacement patients. Methods: The study evaluated 210 overweight/obese patients from the Osteoarthritis Initiative who underwent a knee replacement during an 8-year longitudinal study. Average annual weight changes during 1- to 2-year intervals prior to, including, and subsequent to knee replacement were categorized as loss (≥−2.5%...
Background: Higher serum adiponectin in systemic lupus erythematosus (SLE) patients mitigates the inflammatory response. Previous studies investigated serum adiponectin level in SLE patients compared with control subjects, yielding inconsistent results. Objective: The aim of this meta-analysis was to assess the difference between serum adiponectin levels in SLE patients compared with control subjects. Methods: MEDLINE, PubMed, EMBASE, and Web of Science were searched from inception to August 31, 2016, to identify all observational studies that examined the relationship between serum adiponectin levels and SLE. The study ...
Conclusions: Interferon λ3, a subtype of type III IFNs, is associated with the extent of lupus activity, in particular with active serosal and cutaneous disease. This association could be mechanistically related to anti-Ro/SSA antibodies.
Conclusions: Around 25% of workers with combination therapy with cs-DMARDs developed PWD in 10 years following the diagnosis of RA. Some factors increase the risk of disability. Permanent work disability generates a relevant society burden and increases health care costs. Therefore, indicators predicting failure of combination therapies with cs-DMARDs might provide clinicians of useful tools for modifying treatments avoiding the disease progression.
Abstract: Axial spondyloarthritis (AxSpA) is an inflammatory spondyloarthritis (SpA) that has significant impact on a patient's life. Symptoms, including fatigue, sleep problems, depression, and sexual dysfunction, can profoundly impact health-related quality of life (HRQoL) and limit work, leisure, and daily activities. Available therapies effectively manage pain and inflammation in early-stage disease, but patients often continue to experience impaired HRQoL. Thus, there remains a need for new therapies with novel mechanisms that can stop disease progression, potentially reverse damage caused by AxSpA and improve HRQoL i...
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