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Asthma drug from the garden center

(University of Bonn) The coralberry could offer new hope for asthmatics: researchers at the University of Bonn have extracted a new kind of active pharmaceutical ingredient from its leaves to combat this widespread respiratory disease. In mice, it almost completely inhibits the characteristic contraction of the airways. The plant itself is not exotic: it can be found in any well-stocked garden center. The study is published in the renowned journal Science Translational Medicine.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Objectives/HypothesisThe goal of the study was to perform a systematic review with meta‐analysis to determine the mean change in the 22‐item Sino‐Nasal Outcome Test (SNOT‐22) across patients who have had endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) in the literature. MethodsA literature search was performed to identify studies that assessed SNOT‐22 scores before and after ESS in adult patients with CRS. A random effects model with inverse variance weighting was used to generate the mean change after surgery, along with the forest plot and 95% confidence interval (CI). The impact of patient‐sp...
Source: The Laryngoscope - Category: ENT & OMF Authors: Tags: Systematic Review Source Type: research
Authors: Norlien KG, Landsteiner A, Carlson A Abstract Cosmetologists face a variety of occupational health and safety challenges. To gather information on respiratory issues related to work as a cosmetologist, licensed cosmetologists were invited by e-mail to participate in a short online survey. The survey collected demographic data, work history, respiratory symptoms, product usage, and health and safety training. Results revealed that while 57% of cosmetologists reported having received training on customer or consumer safety, only 10.5% had received training on worker health such as work-related asthma and/or ...
Source: Journal of Environmental Health - Category: Environmental Health Tags: J Environ Health Source Type: research
Summary Fungal sensitisation in adults is associated with severe asthma but prevalence and clinical significance of fungal sensitisation remains unclear in paediatric population. The aim of this study was to study the association of fungal sensitisation with disease severity in children with persistent asthma. One hundred children with persistent asthma in age group 7‐15 years, symptom duration>2 years and forced expiratory volume in first second>50% of expected were enrolled. Skin prick test (SPT) to 8 fungal antigens and total serum immunoglobulin E (IgE) were done. Fungal sensitisation was described as...
Source: Mycoses - Category: Research Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract Asthma is a chronic pulmonary disease that affects an estimated 235 million people worldwide, but asthma drugs have many adverse effects. Opuntia humifusa (eastern prickly pear) has been used as a food and traditional medicine worldwide; however, its anti-asthmatic effects have not been reported. We evaluated O. humifusa as a potential therapeutic or preventive component of anti-asthmatic drugs. We divided ovalbumin-sensitized mice into the following groups: normal control, asthma-induced control, dexamethasone-treated group (positive control), 50 mg/kg O. humifusa-treated group, 100 mg/kg O. hu...
Source: Food and Nutrition Research - Category: Nutrition Authors: Tags: Food Nutr Res Source Type: research
MOULD and damp in the home could cause a number of respiratory diseases, including asthma, bronchitis and lung disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
To determine whether 2 doses of dexamethasone is as effective as 5 days of prednisolone/prednisone therapy in improving symptoms and quality of life of children with asthma exacerbations admitted to the emergency department (ED).
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Articles Source Type: research
ConclusionThe strong correlation suggests that the RCAT alone is equivalent to the RQLQ with respect to patients’ symptom control and quality of life. Patients with uncontrolled symptoms can be identified using the RCAT. Hence, the physician can decide whether symptomatic therapy can be intensified or allergy immunotherapy should be administered.This article is protected by copyright. All rights reserved.
Source: Allergy - Category: Allergy & Immunology Authors: Tags: Original Article: Airway Diseases Source Type: research
Objective: We use a single-alveolar-compartment model to describe the partial pressure of carbon dioxide in exhaled breath, as recorded in time-based capnography. Respiratory parameters are estimated using this model, and then related to the clinical status of patients with obstructive lung disease. Methods: Given appropriate assumptions, we derive an analytical solution of the model, describing the exhalation segment of the capnogram. This solution is parametrized by alveolar CO2 concentration, dead-space fraction, and the time constant associated with exhalation. These quantities are estimated from individual capnogram d...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
A short story about wearable sensors, predictive algorithms and their potential ethical consequences. 35-year-old Susanne Wolfort won a historic court battle against Japanese Shinsai Motors Corporation Monday, as the Court of Appeals in California approved her claim of $18 million compensating for her losses since the company fired her based on changes in her GoSportsLive wearable patch data indicating her pregnancy far earlier as she planned to announce it to Shinsai’s San Francisco, California-based HR department. The court raised the initial sum from $15 million to $18 million as compensation for the damage ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Medical Science Fiction data privacy digital health future pregnancy scifi short story wearable Source Type: blogs
Annals of the American Thoracic Society,Volume 14, Issue Supplement_5, Page S316-S325, November 2017.
Source: Annals of the American Thoracic Society - Category: Respiratory Medicine Authors: Source Type: research
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