Highly sensitive detection of ESR1 mutations in cell-free DNA from patients with metastatic breast cancer using molecular barcode sequencing

Conclusion In conclusion, MB –NGS could successfully detectESR1 mutations in cfDNA with a higher sensitivity of 0.1% than conventional NGS and was considered as clinically useful as ddPCR.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research