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Targeting Inhibition of SmpB by Peptide Aptamer Attenuates the Virulence to Protect Zebrafish against Aeromonas veronii Infection

Peng Liu, Dongyi Huang, Xinwen Hu, Yanqiong Tang, Xiang Ma, Rihui Yan, Qian Han, Jianchun Guo, Yueling Zhang, Qun Sun, Zhu Liu
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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ConclusionsPresence of virulence and resistance genes in A. hydrophila from food sources poses a serious threat to public health. To our knowledge, this is the first report describing the occurrence of A. hydrophila in mullet and highlighting the coexistence of virulence and β‐lactam resistance genes encoded by these bacteria. SignificanceThis data provides insights into the potential association of antimicrobial resistance and virulence genes in A. hydrophila from marketed mullet in Egypt, which could pose threats to humans even if a weak positive correlation exists between both genes.This article is protected by c...
Source: Journal of Applied Microbiology - Category: Microbiology Authors: Tags: Original Article Source Type: research
Publication date: July 2018 Source:Food Control, Volume 89 Author(s): Xinran Lv, Huanhuan Ma, Mengtong Sun, Yang Lin, Fengling Bai, Jianrong Li, Bolin Zhang A novel bacteriocin DY4-2 was produced by strain DY4-2 which was isolated from cutlassfish (Trichiurus lepturus) and identified as Lactobacillus plantarum. This bacteriocin reached the maximum production at stationary phase after 24 h incubation. It was purified by ethyl acetate extraction followed by ultrafiltration, Sephadex G25 chromatography and high-performance liquid chromatography. The molecular mass of bacteriocin DY4-2 was determined as 1465 Da by matrix-...
Source: Food Control - Category: Food Science Source Type: research
Conclusion CTSC plays roles in the immune response to bacterial infection, which provided valuable information for further studying the functions of CTSC in salamander.
Source: Electronic Journal of Biotechnology - Category: Biotechnology Source Type: research
In this study, we identified multiple copies of Rnase2 (six) and Rnase3 (three) in the M. amblycephala genome. The nine genes all possess characteristics typical of the RnaseA superfamily. No expression was detected in the early developmental stages, while a weak expression was observed at 120 and 140 h post-fertilization (hpf) for Rnase2b, Rnase2c, Rnase2e and Rnase3a, suggesting that only three copies of Rnase2 and one of Rnase3 are expressed. Interestingly, only Rnase2e was up-regulated in the kidney of M. amblycephala after Aeromonas hydrophila infection, while Rnase3a was significantly up-regulated in liver, gut and b...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
This article is protected by copyright. All rights reserved. RutG is a broad‐specificity uracil/thymine permease encoded in the pyrimidine utilization operon of enterobacteria. An essential difference from the closely related UraA and other uracil‐specific permeases is the absence of a crucial Phe that is predicted to hinder coordination of thymine at the binding site. Replacing this Phe with Ala allows high‐affinity binding and/or transport of thymine in addition to uracil.
Source: Molecular Microbiology - Category: Microbiology Authors: Tags: Research Article Source Type: research
Publication date: 15 May 2018 Source:Journal of Hazardous Materials, Volume 350 Author(s): Yanting Zhao, Xu-xiang Zhang, Zhonghua Zhao, Cuilan Duan, Huangen Chen, Miaomiao Wang, Hongqiang Ren, Ying Yin, Lin Ye Antibiotic resistance disseminating from animals and their environments is a public issue that poses significant threats to human health. In the present study, the diversity and abundance of antibiotic resistance genes (ARGs) in 15 samples from the guts and related aquaculture environments (water and sediment) of shrimp were investigated. In total, 60 ARGs, 102 ARGs and 67 ARGs primarily belonging to 13, 15 and 15 d...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
This study evaluated the effects of chitosan oligosaccharides (COS) on the changes in quality and microbiota of silver carp fillets stored at 4 °C. During storage, 1% (w/v) COS treated samples maintained good quality, as evidenced by retarding sensory deterioration, inhibiting microbial growth, attenuating the production of total volatile basic nitrogen, putrescine, cadaverine and hypoxanthine, and delaying degradation of inosine monophosphate and hypoxanthine ribonucleotide. Meanwhile, variability in the predominant microbiota in different samples was investigated by culture-dependent and -independent methods. Based...
Source: International Journal of Food Microbiology - Category: Food Science Authors: Tags: Int J Food Microbiol Source Type: research
Microbial Drug Resistance , Vol. 0, No. 0.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
Publication date: 5 May 2018 Source:Journal of Hazardous Materials, Volume 349 Author(s): Xin-Lei Gao, Ming-Fei Shao, Qing Wang, Li-Tao Wang, Wen-Yan Fang, Feng Ouyang, Ji Li Clinically relevant antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in bioaerosols have become a greater threat to public health. However, few reports have shown that ARB and ARGs were found in the atmosphere. High-throughput sequencing applied to environmental sciences has enhanced the exploration of microbial populations in atmospheric samples. Thus, five nosocomial bioaerosols were collected, and the dominant microbial a...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Publication date: March 2018 Source:Aquatic Toxicology, Volume 196 Author(s): Valérie Cornet, Abderrahim Ouaach, S.N.M. Mandiki, Enora Flamion, Aline Ferain, Mélusine Van Larebeke, Benjamin Lemaire, Felipe E. Reyes López, Lluis Tort, Yvan Larondelle, Patrick Kestemont Nutrition is crucial to grow healthy fish particularly in a context of pollution, overcrowding and pathogen risks. Nowadays, the search for food components able to improve fish health is increasingly developing. Here, the influence of four dietary polyunsaturated fatty acids (PUFAs) that are alpha-linolenic acid (ALA, 18:3n-3), linoleic ...
Source: Aquatic Toxicology - Category: Toxicology Source Type: research
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